Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus
…, SY Park, BA Pons-Estel, RH Scofield, AM Stevens… - Nature …, 2011 - nature.com
Systemic lupus erythematosus (SLE, MIM152700) is an autoimmune disease characterized
by self-reactive antibodies resulting in systemic inflammation and organ failure. TNFAIP3, …
by self-reactive antibodies resulting in systemic inflammation and organ failure. TNFAIP3, …
Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort
…, RP Kimberly, E Brown, J Edberg, AM Stevens… - Genes & …, 2011 - nature.com
Systemic lupus erythematosus (SLE) is a prototypic autoimmune disorder with a complex
pathogenesis in which genetic, hormonal and environmental factors have a role. Rare …
pathogenesis in which genetic, hormonal and environmental factors have a role. Rare …
[HTML][HTML] Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility
…, JT Merrill, LA Criswell, RH Scofield, AM Stevens… - PLoS …, 2011 - journals.plos.org
Systemic lupus erythematosus (SLE), a complex polygenic autoimmune disease, is associated
with increased complement activation. Variants of genes encoding complement regulator …
with increased complement activation. Variants of genes encoding complement regulator …
[PDF][PDF] Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study
…, RH Scofield, YW Song, AM Stevens… - The American Journal of …, 2012 - cell.com
Systemic lupus erythematosus (SLE) is a chronic heterogeneous autoimmune disorder
characterized by the loss of tolerance to self-antigens and dysregulated interferon responses. …
characterized by the loss of tolerance to self-antigens and dysregulated interferon responses. …
Maternal microchimerism in peripheral blood in type 1 diabetes and pancreatic islet β cell microchimerism
…, NC Lambert, AM Stevens… - Proceedings of the …, 2007 - National Acad Sciences
Maternal cells have recently been found in the circulation and tissues of mothers' immune-competent
children, including in adult life, and is referred to as maternal microchimerism (MMc)…
children, including in adult life, and is referred to as maternal microchimerism (MMc)…
Myocardial-tissue-specific phenotype of maternal microchimerism in neonatal lupus congenital heart block
AM Stevens, HM Hermes, JC Rutledge, JP Buyon… - The Lancet, 2003 - thelancet.com
Background During pregnancy, maternal cells pass into the fetus, where they can persist for
many years after birth. We investigated the presence of maternal cells in neonatal lupus …
many years after birth. We investigated the presence of maternal cells in neonatal lupus …
Male microchimerism in women without sons: quantitative assessment and correlation with pregnancy history
…, LS Loubiere, MM Madeleine, AM Stevens… - The American journal of …, 2005 - Elsevier
PURPOSE: Fetal microchimerism, derived from fetal cells that persist after pregnancy, is
usually evaluated by tests for male microchimerism in women who gave birth to sons. We …
usually evaluated by tests for male microchimerism in women who gave birth to sons. We …
[HTML][HTML] MicroRNA-3148 modulates allelic expression of toll-like receptor 7 variant associated with systemic lupus erythematosus
…, TB Niewold, JT Merrill, LA Criswell, AM Stevens… - PLoS …, 2013 - journals.plos.org
We previously reported that the G allele of rs3853839 at 3′untranslated region (UTR) of
Toll-like receptor 7 (TLR7) was associated with elevated transcript expression and increased …
Toll-like receptor 7 (TLR7) was associated with elevated transcript expression and increased …
Normally occurring NKG2D+CD4+ T cells are immunosuppressive and inversely correlated with disease activity in juvenile-onset lupus
…, SR Riddell, TA Gooley, AM Stevens… - Journal of Experimental …, 2009 - rupress.org
The NKG2D receptor stimulates natural killer cell and T cell responses upon engagement of
ligands associated with malignancies and certain autoimmune diseases. However, …
ligands associated with malignancies and certain autoimmune diseases. However, …
Fine mapping of Xq28: both MECP2 and IRAK1 contribute to risk for systemic lupus erythematosus in multiple ancestral groups
Objectives The Xq28 region containing IRAK1 and MECP2 has been identified as a risk locus
for systemic lupus erythematosus (SLE) in previous genetic association studies. However, …
for systemic lupus erythematosus (SLE) in previous genetic association studies. However, …