The chemokine CXCL12 regulates monocyte-macrophage differentiation and RUNX3 expression

L Sánchez-Martín, A Estecha… - Blood, the Journal of …, 2011 - ashpublications.org
Monocytes are versatile cells that can express different functional programs in response to
microenvironmental signals. We show that primary blood monocytes secrete the CXCL12 …

Moesin orchestrates cortical polarity of melanoma tumour cells to initiate 3D invasion

A Estecha, L Sánchez-Martín… - Journal of cell …, 2009 - journals.biologists.com
Tumour cell dissemination through corporal fluids (blood, lymph and body cavity fluids) is a
distinctive feature of the metastatic process. Tumour cell transition from fluid to adhesive …

Rho/ROCK and myosin II control the polarized distribution of endocytic clathrin structures at the uropod of moving T lymphocytes

…, L Sánchez-Martín, A Estecha… - Journal of cell …, 2007 - journals.biologists.com
We have examined the spatio-temporal dynamics of clathrin-mediated endocytosis (CME)
during T lymphocyte polarization and migration. Near the plasma membrane, we detected …

[HTML][HTML] RUNX3 regulates intercellular adhesion molecule 3 (ICAM-3) expression during macrophage differentiation and monocyte extravasation

A Estecha, N Aguilera-Montilla, P Sanchez-Mateos… - PloS one, 2012 - journals.plos.org
The adhesion molecule ICAM-3 belongs to the immunoglobulin gene superfamily and functions
as a ligand for the β2 integrins LFA-1, Mac-1 and α d β 2 . The expression of ICAM-3 is …

[HTML][HTML] Mesenchymal contribution to recruitment, infiltration, and positioning of leukocytes in human melanoma tissues

R Samaniego, A Estecha, M Relloso, N Longo… - Journal of Investigative …, 2013 - Elsevier
To understand factors that regulate leukocyte entry and positioning within human melanoma
tissues, we performed a multiparametric quantitative analysis of two separated regions: the …

Anti-cyclic citrullinated peptide versus anti-Sa antibodies in diagnosis of rheumatoid arthritis in an outpatient clinic for connective tissue disease and spondyloarthritis.

…, S Sánchez-Ramón, A Estecha… - The Journal of …, 2006 - jrheum.org
OBJECTIVE: . To compare the diagnostic value of anti-cyclic citrullinated peptide (anti-CCP)
and anti-Sa antibodies in serum for prediction of rheumatoid arthritis (RA) in an outpatient …

Epitope mapping on the dendritic cell-specific ICAM-3-grabbing non-integrin (DC-SIGN) pathogen-attachment factor

E Sierra-Filardi, A Estecha, R Samaniego… - Molecular …, 2010 - Elsevier
DC-SIGN (dendritic cell-specific ICAM-3-grabbing non-integrin) is a myeloid pathogen-attachment
factor C-type lectin which recognizes mannose- and fucose-containing …

[CITATION][C] Association of anti–cyclic citrullinated peptide and anti‐Sa/citrullinated vimentin autoantibodies in rheumatoid arthritis

…, S Sánchez‐Ramón, A Estecha… - Arthritis Care & …, 2006 - Wiley Online Library
Methods. The CCP IgG assay was performed using synthetic CCP enzyme immunoassay
technology (CCP-2;

[HTML][HTML] Viral RNA load in plasma is associated with critical illness and a dysregulated host response in COVID-19

…, I Fernández Natal, G Megías, M González-Estecha… - Critical Care, 2020 - Springer
Background COVID-19 can course with respiratory and extrapulmonary disease. SARS-CoV-2
RNA is detected in respiratory samples but also in blood, stool and urine. Severe COVID-…

[HTML][HTML] Phase angle and rectus femoris cross-sectional area as predictors of severe malnutrition and their relationship with complications in outpatients with post …

…, C Reina-Artacho, MA Estecha-Foncea… - Frontiers in …, 2023 - frontiersin.org
Background and aims The diagnosis of malnutrition in post-critical COVID-19 patients is
challenging as a result of the high prevalence of obesity, as well as the variability and previously …