Efficacy and safety of an interleukin 6 monoclonal antibody for the treatment of systemic lupus erythematosus: a phase II dose-ranging randomised controlled trial
…, JT Merrill, S Popa, AJ Spindler, A Eimon… - Annals of the …, 2017 - ard.bmj.com
Objectives This phase II trial evaluated the efficacy and safety of an interleukin (IL) 6 monoclonal
antibody for systemic lupus erythematosus (SLE). Methods Patients with active disease …
antibody for systemic lupus erythematosus (SLE). Methods Patients with active disease …
Monocytes from Sjögren's syndrome patients display increased vasoactive intestinal peptide receptor 2 expression and impaired apoptotic cell phagocytosis
V Hauk, L Fraccaroli, E Grasso, A Eimon… - Clinical & …, 2014 - academic.oup.com
Sjögren's syndrome (SS) is a chronic autoimmune disease characterized by salivary and
lacrimal gland dysfunction. Clinical observations and results from animal models of SS support …
lacrimal gland dysfunction. Clinical observations and results from animal models of SS support …
Rheumatoid arthritis in Latin Americans enriched for Amerindian ancestry is associated with loci in chromosomes 1, 12, and 13, and the HLA class II region
…, LJ Catoggio, G Tate, A Eimon… - Arthritis & …, 2013 - Wiley Online Library
Objective To identify susceptibility loci for rheumatoid arthritis (RA) in Latin American
individuals with admixed European and Amerindian genetic ancestry. Methods Genotyping was …
individuals with admixed European and Amerindian genetic ancestry. Methods Genotyping was …
Analysis of IRF5 gene functional polymorphisms in rheumatoid arthritis
…, IF Petersson, A Eimon… - … : Official Journal of …, 2006 - Wiley Online Library
Objective Recent findings suggest that interferon regulatory factor 5 (IRF‐5) may play a
crucial role in several cellular processes, including the transcription of genes for inflammatory …
crucial role in several cellular processes, including the transcription of genes for inflammatory …
Study of functional variants of the BANK1 gene in rheumatoid arthritis
…, I Petersson, B Pons‐Estel, A Eimon… - … : Official Journal of …, 2009 - Wiley Online Library
Objective To investigate 1 functional (rs17266594) and 2 potentially functional (rs10516487
and rs3733197) BANK1 variants, which were previously identified as systemic lupus …
and rs3733197) BANK1 variants, which were previously identified as systemic lupus …
[PDF][PDF] Elevated IL-1β levels in anti-Ro/SSA connective tissue diseases patients with prolonged corrected QTc interval
Objective Patients with systemic lupus erythematosus (SLE) and primary Sjögren’s syndrome
(pSS) have increased IL-1β levels. IL-1β and other pro-inflammatory cytokines have a …
(pSS) have increased IL-1β levels. IL-1β and other pro-inflammatory cytokines have a …
4G/5G plasminogen activator inhibitor-1 and− 308 A/G tumor necrosis factor-α promoter gene polymorphisms in Argentinean lupus patients: focus on lupus nephritis
…, R Trobo, A Alvarez, A Eimon… - Clinical and …, 2014 - Springer
We investigated the relationship between the 4G/5G plasminogen activator inhibitor (PAI-1)
and −308 A/G tumor necrosis factor-α (TNF-α) polymorphisms and the clinical and …
and −308 A/G tumor necrosis factor-α (TNF-α) polymorphisms and the clinical and …
[PDF][PDF] The-2518 A/G polymorphism in the monocyte chemoattractant protein 1 gene is associated with the risk of developing systemic lupus erythematosus in …
…, A Allievi, A Orden, R Trobo, A Alvarez, A Eimon… - Eur Cytokine …, 2012 - academia.edu
Systemic lupus erythematosus (SLE) is a systemic, autoimmune disorder. Monocyte
chemoattractant protein 1 (MCP-1), a chemokine involved in the recruitment and migration of …
chemoattractant protein 1 (MCP-1), a chemokine involved in the recruitment and migration of …
[PDF][PDF] Impacto de las Guías de Práctica Clínica para el Tratamiento de la Artritis Reumatoidea
…, V Juarez, J Rosa, D Pereira, A Eimon… - Revista Argentina de …, 2012 - redalyc.org
Introducción: Las Guías de Práctica Clínica (GPC) son necesarias para un íntegro abordaje
del paciente. Este estudio se propuso evaluar el impacto de las GPC en Artritis …
del paciente. Este estudio se propuso evaluar el impacto de las GPC en Artritis …
Effects of Amerindian genetic ancestry on clinical variables and therapy in patients with rheumatoid arthritis
…, JLC Moreno, LJ Catoggio, G Tate, A Eimon… - The Journal of …, 2017 - jrheum.org
Objective. To define whether Amerindian genetic ancestry correlates with clinical and
therapeutic variables in admixed individuals with rheumatoid arthritis (RA) from Latin America. …
therapeutic variables in admixed individuals with rheumatoid arthritis (RA) from Latin America. …