[HTML][HTML] Impaired immune cell cytotoxicity in severe COVID-19 is IL-6 dependent

…, C Lazzeri, A Matucci, A Vultaggio… - The Journal of …, 2020 - Am Soc Clin Investig
BACKGROUND Coronavirus disease 19 (COVID-19) is an emerging infectious disease
caused by SARS-CoV-2. Antiviral immune response is crucial to achieve pathogen clearance; …

[HTML][HTML] Is IgE or eosinophils the key player in allergic asthma pathogenesis? Are we asking the right question?

A Matucci, A Vultaggio, E Maggi, I Kasujee - Respiratory research, 2018 - Springer
Bronchial asthma (BA) is a chronic inflammatory disease with a marked heterogeneity in
pathophysiology and etiology. The heterogeneity of BA may be related to the inducing …

Considerations on biologicals for patients with allergic disease in times of the COVID‐19 pandemic: an EAACI statement

A Vultaggio, I Agache, CA Akdis, M Akdis, S Bavbek… - Allergy, 2020 - Wiley Online Library
The outbreak of the SARS‐CoV‐2‐induced coronavirus disease 2019 (COVID‐19) pandemic
re‐shaped doctor‐patient interaction and challenged capacities of healthcare systems. It …

[HTML][HTML] Systematic review of safety and efficacy of rituximab in treating immune-mediated disorders

…, B Wuest, J Schreiner, UC Steiner, A Vultaggio… - Frontiers in …, 2019 - frontiersin.org
Background: During the past years biologic agents (also termed biologicals or biologics)
have become a crucial treatment option in immunological diseases. Numerous articles have …

[HTML][HTML] Clinical outcome, incidence, and SARS-CoV-2 infection-fatality rates in Italian patients with inborn errors of immunity

…, G Giardino, A Punziano, A Vultaggio… - The Journal of …, 2021 - jaci-inpractice.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-positive patients with
inborn errors of immunity (IEI) showed a similar infection-fatality rate, a lower incidence in …

Acute infusion reactions induced by monoclonal antibody therapy

E Maggi, A Vultaggio, A Matucci - Expert review of clinical …, 2011 - Taylor & Francis
This article reports recent evidence on epidemiological data concerning monoclonal antibody
(mAb) infusion-related anaphylaxis, as well as recent data on the correlation between …

Defective production of LIF, M-CSF and Th2-type cytokines by T cells at fetomaternal interface is associated with pregnancy loss

MP Piccinni, C Scaletti, A Vultaggio, E Maggi… - Journal of reproductive …, 2001 - Elsevier
Development of CD4+ helper T (Th) cells into type 1 (Th1) or type 2 (Th2) effectors can be
influenced by hormones enhanced during pregnancy. Progesterone, at concentrations …

Th2‐oriented profile of male offspring T cells present in women with systemic sclerosis and reactive with maternal major histocompatibility complex antigens

C Scaletti, A Vultaggio, S Bonifacio… - Arthritis & …, 2002 - Wiley Online Library
Objective To characterize the cytokine production profile of male‐offspring T cells reactive
against maternal major histocompatibility complex (MHC) antigens present in the peripheral …

Prompt predicting of early clinical deterioration of moderate-to-severe COVID-19 patients: usefulness of a combined score using IL-6 in a preliminary study

A Vultaggio, E Vivarelli, G Virgili, E Lucenteforte… - The Journal of Allergy …, 2020 - Elsevier
Background The early identification of patients at risk of clinical deterioration is of interest
considering the timeline of COVID-19 after the onset of symptoms. Objective The aim of our …

[HTML][HTML] Asthma in a large COVID-19 cohort: prevalence, features, and determinants of COVID-19 disease severity

M Caminati, A Vultaggio, A Matucci, G Senna… - Respiratory …, 2021 - Elsevier
Background Asthma prevalence among COVID-19 patients seems to be surprisingly low.
However the clinical profile of COVID-19 asthmatic patients and potential determinants of …