Autoreactivity of peripheral helper T cells in the joints of rheumatoid arthritis

T Sakuragi, H Yamada, A Haraguchi, K Kai… - The Journal of …, 2021 - journals.aai.org
Autoreactive CD4 T cells are thought to play pivotal roles in the pathogenesis of rheumatoid
arthritis (RA). Recently, a subset of CD4 T cells that express high levels of programmed …

[HTML][HTML] Factors affecting patient satisfaction related to cost and treatment effectiveness in rheumatoid arthritis: results from the multicenter observational cohort study …

T Fujiwara, M Kondo, H Yamada, A Haraguchi… - Arthritis Research & …, 2022 - Springer
Background To further improve rheumatoid arthritis (RA) treatment, it is necessary to
understand each RA patient’s satisfaction and to identify the factors affecting their satisfaction. …

Th1 is the predominant helper T cell subset that produces GM-CSF in the joint of rheumatoid arthritis

H Yamada, A Haraguchi, K Sakuraba, K Okazaki… - RMD open, 2017 - rmdopen.bmj.com
RMD Open contrast, nearly 80% of GM-CSF-producing CD4 T cells in the joint produced IFN-γ.
The frequency of GM-CSF-producing cells within IFN-γ-producing cells was also higher …

High prevalence of cam deformity in dysplastic hips: A three‐dimensional CT study

…, D Hara, M Kanazawa, A Haraguchi… - Journal of …, 2016 - Wiley Online Library
Cam deformity could lead to suboptimal articulation by causing secondary femoroacetabular
impingement after periacetabular osteotomy; however, the inherent femoral head‐neck …

Have the radiographic characteristics of total knee arthroplasty recipients in rheumatoid arthritis changed after the induction of biologic disease modifying …

K Fujimura, A Haraguchi, R Sakurai… - Modern …, 2022 - academic.oup.com
Objectives Whether the characteristics of patients with rheumatoid arthritis (RA) undergoing
total knee arthroplasty (TKA) have changed in the era of biologic disease-modifying …

Prevalence of spondyloarthritis symptom in inflammatory bowel disease patients: a questionnaire survey

K Kamo, T Shuto, A Haraguchi - Modern Rheumatology, 2015 - academic.oup.com
Objectives. We clarified the prevalence of spondyloarthritis (SpA) symptom in inflammatory
bowel disease (IBD). Methods. We performed the questionnaire survey of SpA symptom in …

Minimum 10-year results of cementless total hip arthroplasty in patients with rheumatoid arthritis

A Haraguchi, Y Nakashima, H Miyahara… - Modern …, 2017 - academic.oup.com
Objectives: To retrospectively evaluate the long-term results of cementless total hip arthroplasty
(THA) in patients with rheumatoid arthritis (RA) and postoperative patient mortality after …

Does Abatacept increase postoperative adverse events in rheumatoid arthritis compared with conventional synthetic disease-modifying drugs?

…, A Nakajima, R Hara, A Haraguchi… - The Journal of …, 2020 - jrheum.org
Objective. To investigate whether abatacept (ABA) causes more adverse events (AE) than
conventional synthetic disease-modifying antirheumatic drugs (csDMARD) after orthopedic …

Impact of methotrexate dose on efficacy of adalimumab in Japanese patients with rheumatoid arthritis: results from registered data analyses

…, T Fukuda, H Harada, A Haraguchi… - Modern …, 2017 - academic.oup.com
Objective: Upper limit of methotrexate (MTX) for patients with rheumatoid arthritis (RA) was
recently increased from 8 to 16 mg/week in Japan. We therefore examined the effect of …

Suppression of joint destruction with subcutaneous tocilizumab for Japanese patients with rheumatoid arthritis in clinical practice

…, T Fukuda, S Ikemura, A Haraguchi - Modern …, 2020 - academic.oup.com
Objectives: To investigate the efficacy of suppressing joint destruction with subcutaneous
tocilizumab (TCZ-SC) for Japanese rheumatoid arthritis (RA) patients in the real-world clinical …