Background: DNA methylation changes are an early event in carcinogenesis and are often
present in the precursor lesions of various cancers. We examined whether DNA methylation …

Background: Clinical practice recommendations state that patients with fragility fractures
should be evaluated for osteoporosis and treated for the disease if it is present. The purpose of …

Curcumin is a natural dietary polyphenol compound that has various pharmacological activities
such as antiproliferative and cancer-preventive activities on tumor cells. Indeed, the role …

Objective. Estimate the accuracy and cost-effectiveness of cervical cancer screening strategies
based on high-risk human papillomavirus (HPV) DNA testing of self-collected vaginal …

Studies examining real-world effectiveness of osteoporosis therapies are beset by limitations
due to confounding by indication. By evaluating longitudinal changes in fracture incidence, …

Purpose Pharmacy commercial claims databases are widely used for pharmacoepidemiologic
research. However, concerns have been raised that these databases may not fully …

The purpose of this work was to evaluate systemic glucocorticoid exposure and fracture among
patients with newly‐diagnosed inflammatory and immune‐modulated conditions. Using …

Our study validated a claims‐based algorithm for the identification of incident and recurrent
fractures in administrative data. We used Centers for Medicare and Medicaid (CMS) claims …

Few data are available on physician perceptions of osteoporosis medication adherence.
This study compared physician-estimated medication adherence with adherence calculated …

The association between bisphosphonate adherence in the first 12months after therapy
initiation and subsequent fracture risk was examined. Patients were identified from a large, …