Objective. To develop and test a new multidimensional questionnaire for assessment of
children with juvenile idiopathic arthritis (JIA) in standard clinical care. Methods. The Juvenile …

Background To our knowledge, the characteristics and burden of childhood arthritis have
never been studied on a worldwide basis. We aimed to investigate, with a cross-sectional study…

Background Behçet’s disease is a rare multi-systemic inflammatory disease with unknown
etiology which involves principally oral and genital mucosa, skin and eyes. Average age at …

One of the most intriguing and mysterious phenomena observed during the COVID-19
pandemic has been represented by the occurrence of the multisystem inflammatory syndrome in …

Background Little evidence-based information is available to guide the treatment of
oligoarticular juvenile idiopathic arthritis. We aimed to investigate whether oral methotrexate …

Objective To develop a composite disease activity score for systemic JIA (sJIA) and to
provide preliminary evidence of its validity. Methods The systemic Juvenile Arthritis Disease …

Objective To compare the long-term disease state, in terms of activity and damage, of children
with juvenile idiopathic arthritis (JIA) who had their disease onset in methotrexate (MTX) or …

Introduction New early low-invasive biomarkers are demanded for the management of
Oligoarticular Juvenile Idiopathic Arthritis (OJIA), the most common chronic pediatric rheumatic …

We describe a 2 year old boy with two previously undescribed frameshift mutations in the
interferon (IFN)α/β receptor 2 (IFNAR2) gene presenting with hemophagocytic …

Background Data from routine clinical practice are needed to further define the efficacy and
safety of biologic medications in children with juvenile idiopathic arthritis (JIA). The aim of …