Clinical and genetic characteristics of type 2 diabetes with and without GAD antibodies.

T Tuomi, A Carlsson, H Li, B Isomaa, A Miettinen… - Diabetes, 1999 - Am Diabetes Assoc
The aim of the study was 1) to establish the prevalence of GAD antibodies (GADab) in a
population-based study of type 2 diabetes in western Finland, 2) to genetically and …

Prevalence and clinical associations of 10 defined autoantibodies in autoimmune polyendocrine syndrome type I

…, H Hedstrand, E Landgren, A Miettinen… - The Journal of …, 2004 - academic.oup.com
The prevalence of autoantibodies against nine intracellular enzyme autoantigens, namely
21-hydroxylase, side-chain cleavage enzyme (SCC), 17α-hydroxylase, glutamic acid …

A defect of regulatory T cells in patients with autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy

…, K Talvensaari, J Perheentupa, A Miettinen… - The Journal of …, 2007 - journals.aai.org
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED), a monogenic
recessive disease characterized by autoimmunity against multiple tissues, offers a unique …

Involvement of lipid rafts in nephrin phosphorylation and organization of the glomerular slit diaphragm

M Simons, K Schwarz, W Kriz, A Miettinen… - The American journal of …, 2001 - Elsevier
NPHS1 has recently been identified as the gene whose mutations cause congenital nephrotic
syndrome of the Finnish type. The respective gene product nephrin is a transmembrane …

Nephrin localizes at the podocyte filtration slit area and is characteristically spliced in the human kidney

…, S Wang, T Palmen, P Luimula, A Miettinen… - The American journal of …, 1999 - Elsevier
Defects in the newly reported gene NPHS1 in chromosome 19 cause the massive proteinuria
of Finnish type congenital nephrotic syndrome (CNF). Together with its gene product, …

Adrenal and steroidal cell antibodies in patients with autoimmune polyglandular disease type I and risk of adrenocortical and ovarian failure

P AHONEN, A MIETTINEN… - The Journal of Clinical …, 1987 - academic.oup.com
Thirty-one patients with autoimmune polyglandular disease type I who initially had no
adrenocortical and/or ovarian failure were followed for 1.2–12.1 yr (mean, 8.3) by determinations …

A prospective study of 63 couples with a history of recurrent spontaneous abortion: contributing factors and outcome of subsequent pregnancies

…, T Palosuo, T Ramsay, A Miettinen… - Human …, 1993 - academic.oup.com
To evaluate the possible causes of recurrent spontaneous abortion (RSA) and to elucidate
the prognosis for subsequent pregnancies 63 RSA patients were studied. Parental karyo-…

Ulex europaeus I lectin as a marker for tumors derived from endothelial cells

M Miettinen, H Holthofer, VP Lehto… - American Journal of …, 1983 - academic.oup.com
Some skin and soft tumors, which generally are assumed to be derived from endothelial
cells or blood vessels, were characterized with fluorochrome-labeled Ulex europaeus I …

Antibodies to glutamic acid decarboxylase and insulin-dependent diabetes in patients with autoimmune polyendocrine syndrome type I.

…, J Perheentupa, A Lernmark, A Miettinen - The Journal of …, 1996 - academic.oup.com
To evaluate the association of autoimmunity to glutamic acid decarboxylase (GAD) with
insulin-dependent diabetes mellitus (IDDM) and IDDM-associated human leukocyte antigen (…

Atrophic gastritis and Helicobacter pylori infection in outpatients referred for gastroscopy

A Oksanen, P Sipponen, R Karttunen, A Miettinen… - Gut, 2000 - gut.bmj.com
BACKGROUND Atrophic gastritis has been shown to be one of the long term sequelae
ofHelicobacter pylori infection. AIMS To determine the prevalence of atrophic gastritis in …