Introduction Systemic sclerosis (SSc) is characterized by fibrosis and microvascular
abnormalities including dysregulated angiogenesis. Chemokines, in addition to their …

Objective. Raynaud’s phenomenon (RP) is an important clinical feature of systemic sclerosis
(SSc) for which consistently effective therapies are lacking. The study was designed to …

Systemic Sclerosis (Scleroderma, SSc) is a disease of unknown etiology characterized by
widespread vasculopathy and extracellular matrix deposition leading to fibrosis and …

Systemic sclerosis- (SSc-) related vasculopathy, as manifested by Raynaud's Phenomenon (RP)
and digital ulcers (DUs), is associated with significant impairment of the quality of life …

Conclusions Digital ulcers and skin thickening had minimal impact whereas tendon
involvement dominated patient ratings of hand function. No significant correlations were found …

PURPOSE: The diagnosis of pulmonary hypertension (PH) in patients with scleroderma
related interstitial lung disease (SILD) is important for patient management. Doppler …

Objective. Few studies exist on sexual activity and functioning in female patients with systemic
sclerosis (SSc, scleroderma). We studied the patientreported impact of SSc on sexual …

Introduction: Systemic sclerosis (SSc) is characterized by fibrosis and microvascular
abnormalities including dysregulated angiogenesis. Chemokines, in addition to their …

Systemic sclerosis (scleroderma or SSc) is a chronic multisystem disorder involving the skin,
joints, gut, lungs, kidney, heart, and blood vessels. It has a profound impact on quality of life …