OBJECTIVE: To assess the effectiveness of methotrexate (MTX) in the treatment of juvenile
idiopathic arthritis (JIA) associated uveitis, which is still one of the most common causes of …

OBJECTIVE: Uveitis occurs in 10%-15% of patients with juvenile idiopathic arthritis (JIA). If
topical treatment fails, second-line agents are used to control the disease. However, some …

Objective. Systemic sclerosis (SSc) is a rare connective tissue disease in childhood. We
compared the characteristics of adult patients with juvenile-onset SSc (jSSc) from a single-…

Objective. To evaluate the effectiveness of leflunomide in children with juvenile idiopathic
arthritis (JIA) as used in actual clinical practice. Methods. We conducted a retrospective review …

Objectives. The modified Rodnan skin score (MRSS) is used as a primary outcome measure
in most therapeutic trials in systemic sclerosis (SSc) in adults. Before we can apply this …

Idiosyncratic drug reactions are rare but serious adverse drug reactions unrelated to the
known therapeutic properties of the drug and manifest in only a small percentage of the treated …

Background: Uveitis occurs in 10-15% of with juvenile idiopathic arthritis (JIA). When treatment
fails, a second-line agent is used to the disease Currently there is no controlled regarding …

Background: Leflunomide (LEF) is a second-line agent not yet licensed for treatment of
juvenile idiopathic arthritis (JIA), despite a Phase?? study showing an effectiveness in treating …

Methods Patients with less than 18 months of disease duration, after the first Non-Raynaud
symptomatic, are prospectively assessed, using a standardized protocol. Results We report …

Background Juvenile systemic sclerosis (jSSc) is a orphan autoimmune disease. Currently
only retrospective data is existing without a standardized assessment regarding the organ …