User profiles for A. SAITO

Akatsuki Saito

University of Miyazaki
Verified email at cc.miyazaki-u.ac.jp
Cited by 4884

Neuronal death/survival signaling pathways in cerebral ischemia

T Sugawara, M Fujimura, N Noshita, GW Kim, A Saito… - NeuroRx, 2004 - Elsevier
Cumulative evidence suggests that apoptosis plays a pivotal role in cell death in vitro after
hypoxia. Apoptotic cell death pathways have also been implicated in ischemic cerebral injury …

[HTML][HTML] TGF-β signaling in lung health and disease

A Saito, M Horie, T Nagase - International journal of molecular sciences, 2018 - mdpi.com
Transforming growth factor (TGF)-β is an evolutionarily conserved pleiotropic factor that
regulates a myriad of biological processes including development, tissue regeneration, immune …

Recent advances in research on cold thermal energy storage

A Saito - International Journal of Refrigeration, 2002 - Elsevier
Recent literatures in the field of cold thermal energy storage (CTES) are reviewed. First, the
concept of the CTES is explained. Examples of load leveling of electrical energy in various …

[HTML][HTML] Altered TMPRSS2 usage by SARS-CoV-2 Omicron impacts infectivity and fusogenicity

…, A Abdullahi, IATM Ferreira, N Goonawardane, A Saito… - Nature, 2022 - nature.com
The SARS-CoV-2 Omicron BA.1 variant emerged in 2021 1 and has multiple mutations in its
spike protein 2 . Here we show that the spike protein of Omicron has a higher affinity for …

Autophagy is activated for cell survival after endoplasmic ReticulumStress

M Ogata, S Hino, A Saito, K Morikawa… - … and cellular biology, 2006 - Taylor & Francis
Eukaryotic cells deal with accumulation of unfolded proteins in the endoplasmic reticulum (ER)
by the unfolded protein response, involving the induction of molecular chaperones, …

[HTML][HTML] Enhanced fusogenicity and pathogenicity of SARS-CoV-2 Delta P681R mutation

A Saito, T Irie, R Suzuki, T Maemura, H Nasser, K Uriu… - Nature, 2022 - nature.com
During the current coronavirus disease 2019 (COVID-19) pandemic, a variety of mutations
have accumulated in the viral genome of severe acute respiratory syndrome coronavirus 2 (…

[PDF][PDF] SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity

C Motozono, M Toyoda, J Zahradnik, A Saito… - Cell host & …, 2021 - cell.com
Many SARS-CoV-2 variants with naturally acquired mutations have emerged. These
mutations can affect viral properties such as infectivity and immune resistance. Although the …

Association of comorbid conditions and mortality in hemodialysis patients in Europe, Japan, and the United States: the Dialysis Outcomes and Practice Patterns Study …

…, RA Wolfe, T Akiba, VE Andreucci, A Saito… - Journal of the …, 2003 - journals.lww.com
ABSTRACT. Mortality rates among hemodialysis patients vary greatly across regions.
Representative databases containing extensive profiles of patient characteristics and outcomes …

[HTML][HTML] Prevention of second primary tumors by an acyclic retinoid, polyprenoic acid, in patients with hepatocellular carcinoma

…, M Ninomiya, S Adachi, A Saito… - … England Journal of …, 1996 - Mass Medical Soc
Background In patients with hepatocellular carcinoma (hepatoma), the rate of recurrent and
second primary hepatomas is high despite surgical resection and percutaneous ethanol-…

[HTML][HTML] In vivo destabilization of dynamic microtubules by HDAC6‐mediated deacetylation

A Matsuyama, T Shimazu, Y Sumida, A Saito… - The EMBO …, 2002 - embopress.org
Trichostatin A (TSA) inhibits all histone deacetylases (HDACs) of both class I and II, whereas
trapoxin (TPX) cannot inhibit HDAC6, a cytoplasmic member of class II HDACs. We took …