User profiles for A. Mordente
Alvaro MordenteProfessore Ordinario di Biochimica, Università Cattolica del S. Cuore Verified email at unicatt.it Cited by 4216 |
Lycopene and cardiovascular diseases: an update
A Mordente, B Guantario, E Meucci… - Current medicinal …, 2011 - ingentaconnect.com
Cardiovascular disease (CVD) is the leading cause of death in Western societies and accounts
for up to a third of all deaths worldwide. In comparison to the Northern European or other …
for up to a third of all deaths worldwide. In comparison to the Northern European or other …
New developments in anthracycline-induced cardiotoxicity
A Mordente, E Meucci, A Silvestrini… - Current medicinal …, 2009 - ingentaconnect.com
Anthracyclines are among the most effective anticancer drugs ever developed. Unfortunately,
their clinical use is severely limited by the development of a progressive dose-dependent …
their clinical use is severely limited by the development of a progressive dose-dependent …
Cancer biomarkers discovery and validation: state of the art, problems and future perspectives
A Mordente, E Meucci, GE Martorana… - Advances in Cancer …, 2015 - Springer
Cancer is one of the major public health problems worldwide representing the leading
cause of morbidity and mortality in industrialized countries. To reduce cancer morbidity and …
cause of morbidity and mortality in industrialized countries. To reduce cancer morbidity and …
Defective plasma antioxidant defenses and enhanced susceptibility to lipid peroxidation in uncomplicated IDDM
…, G Marra, B Giardina, P Cotroneo, A Mordente… - Diabetes, 1997 - Am Diabetes Assoc
Oxidative stress is postulated to be increased in patients with IDDM. Accumulating evidence
suggests that oxidative cell injury caused by free radicals contributes to the development of …
suggests that oxidative cell injury caused by free radicals contributes to the development of …
Doxorubicin metabolism and toxicity in human myocardium: role of cytoplasmic deglycosidation and carbonyl reduction
S Licata, A Saponiero, A Mordente… - Chemical research in …, 2000 - ACS Publications
The anthracycline doxorubicin (DOX) is an exceptionally good antineoplastic agent, but its
use is limited by formation of metabolites which induce acute and chronic cardiac toxicities. …
use is limited by formation of metabolites which induce acute and chronic cardiac toxicities. …
The secondary alcohol metabolite of doxorubicin irreversibly inactivates aconitase/iron regulatory protein‐1 in cytosolic fractions from human myocardium
Anticancer therapy with doxorubicin (DOX) is limited by severe cardiotoxicity, presumably
reflecting the intramyocardial formation of drug metabolites that alter cell constituents and …
reflecting the intramyocardial formation of drug metabolites that alter cell constituents and …
[HTML][HTML] Metal-catalyzed oxidation of human serum albumin: conformational and functional changes. Implications in protein aging.
E Meucci, A Mordente, GE Martorana - Journal of Biological Chemistry, 1991 - Elsevier
Mild oxidative stress, as elicited by ascorbate, oxygen, and trace metals, affects the binding
properties of human serum albumin via purely conformational changes. In fact, no gross …
properties of human serum albumin via purely conformational changes. In fact, no gross …
Effect of smoking one cigarette on antioxidant metabolites in the saliva of healthy smokers
Concentrations of glutathione, uric acid and total antioxidant activity, expressed as Trolox (a
water-soluble vitamin E analogue) equivalent, were measured in the saliva of healthy non-…
water-soluble vitamin E analogue) equivalent, were measured in the saliva of healthy non-…
Oxidative stress and overexpression of manganese superoxide dismutase in patients with Alzheimer's disease
…, S Borrello, M Passantino, B Palazzotti, A Mordente… - Neuroscience …, 1998 - Elsevier
Substantial evidence supports the hypothesis that oxygen free radicals are involved in various
neurodegenerative disorders. To assess the presence of oxidative stress in Alzheimer's …
neurodegenerative disorders. To assess the presence of oxidative stress in Alzheimer's …
Antioxidant properties of 2, 3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1, 4-benzoquinone (idebenone)
A Mordente, GE Martorana, G Minotti… - Chemical research in …, 1998 - ACS Publications
Idebenone [2,3-dimethoxy-5-methyl-6-(10-hydroxydecyl)-1,4-benzoquinone] is a synthetic
analogue of coenzyme Q that is currently employed in the treatment of vascular and …
analogue of coenzyme Q that is currently employed in the treatment of vascular and …