FÖrster resonance energy transfer (FRET)-based biosensors have achieved great success
for biological applications. However, what is not extensively appreciated is the growing role …

Rhubarb is one of the most ancient, commonly used and important herbs in Chinese medicine.
The modern researches of rhubarb clarified the efficacies, ingredients and mechanisms …

Collagen induced arthritis (CIA) is an autoimmune model that in many ways resembles
rheumatoid arthritis (RA). Immunization of genetically susceptible strains of rodents and primates …

Background The current influenza pandemic calls for a safe and effective vaccine. We
assessed the safety and immunogenicity of eight formulations of 2009 pandemic influenza A …

We have found that intradermal injection of native type II collagen extracted from human,
chick or rat cartilage induces an inflammatory arthritis in approximately 40% of rats of several …

Although deep learning has revolutionized protein structure prediction, almost all experimentally
characterized de novo protein designs have been generated using physically based …

A phagemid system was developed for the monovalent display of combinatorial antibody
Fab libraries on the surface of filamentous phage M13. Fab fragments were fused to the …

Gastrointestinal (GI) tract damage by chemotherapy or radiation limits their efficacy in cancer
treatment. Radiation has been postulated to target epithelial stem cells within the crypts of …

Transforming growth factor beta (TGF-beta) is a potent chemoattractant in vitro for human
dermal fibroblasts. Intact disulfide and perhaps the dimeric structure of TGF-beta is essential for …

The chemotactice response of human dermal fibroblasts of type I, II, and III human collagens
and collagen-derived peptides was quantitated by an in vitro assay. All three native human …