It has become clear that, together with deregulated growth, inhibition of programmed cell
death (PCD) plays a pivotal role in tumorigenesis. In this review, we present an overview of the …

This review examines the evidence for longitudinal predictors of substance use and abuse
in emerging adulthood. Nationally representative data from the 2007 National Survey on …

▪ Abstract The guidance of axons during the establishment of the nervous system is mediated
by a variety of extracellular cues that govern cytoskeletal dynamics in axonal growth cones. …

MicroRNA (miRNA) species (miR) regulate mRNA translation and are implicated as
mediators of disease pathology via coordinated regulation of molecular effector pathways. …

The proinflammatory cytokine IL-17A is considered a crucial player in rheumatoid arthritis (RA)
pathogenesis. In experimental models of autoimmune arthritis, it has been suggested that …

Rationale: Chronic low-grade inflammation involving adipose tissue likely contributes to the
metabolic consequences of obesity. The cytokine interleukin (IL)-33 and its receptor ST2 are …

CD95 is the quintessential death receptor and, when it is bound by ligand, cells undergo
apoptosis. Recent evidence suggests, however, that CD95 mediates not only apoptosis but …

Objective Anticitrullinated protein antibodies (ACPA) are a major risk factor for bone loss in
rheumatoid arthritis (RA). We have recently shown that ACPA directly induce bone loss by …

The checkpoints and mechanisms that contribute to autoantibody-driven disease are as yet
incompletely understood. Here we identified the axis of interleukin 23 (IL-23) and the T H 17 …

Microparticles are small membrane vesicles released from the cell membrane by exogenous
budding. To elucidate the interactions of microparticles with macrophages, the effect of …