Several decades of basic and clinical research have demonstrated that there is an association
between the insulin-like growth factors (IGFs) and neoplasia. We begin with a brief …

The role of vascular endothelial growth factor (VEGF) in renal pathophysiology. Vascular
endothelial growth factor (VEGF) is an endothelial-specific growth factor that promotes …

Accumulating epidemiological evidence shows that being either overweight or obese, in other
words having excess body weight (EBW), is associated with an increased risk of several, …

Diabetes and cardiovascular diseases (CVD) often appear as the two sides of a coin: on
one side, diabetes mellitus (DM) has been rated as an equivalent of coronary heart disease (…

Diabetic nephropathy in type 2 diabetic patients is a frequent complication associated with
increased morbidity and mortality. Various growth factors and cytokines have been implicated …

We hypothesized that an acute bout of strenuous, non‐damaging exercise would increase
rates of protein synthesis of collagen in tendon and skeletal muscle but these would be less …

Background— Recent studies have suggested that higher body mass index (BMI) is associated
with improved prognosis in chronic heart failure (CHF). The adipocytokine adiponectin is …

GH participates in growth, metabolism, and cellular differentiation. To study these roles, we
previously generated two different dwarf mouse lines, one expressing a GH antagonist (GHA) …

At present, diabetic kidney disease affects about 15–25% of type 1 and 30–40% of type 2
diabetic patients. Several decades of extensive research has elucidated various pathways to …

Culture of osteogenic cells on a porous scaffold could offer a new solution to bone grafting
using autologous human mesenchymal stem cells (hMSC) from the patient. We compared …