Determination of reference values of MDR‐ABC transporter activities in CD3+ lymphocytes of healthy volunteers using a flow cytometry based method

…, K Tauberne Jakab, S Baráth, A Apjok… - Cytometry Part B …, 2019 - Wiley Online Library
Background MDR transporters are important biomarkers of drug resistance in cancer and in
autoimmune conditions. We determined the MDR1, MRP1 and BCRP activity in CD3+ …

Peripheral lymphocyte multidrug resistance activity as a predictive tool of biological therapeutic response in rheumatoid arthritis

G Toldi, P Batel, S Baráth, P Szerémy, A Apjok… - The Journal of …, 2019 - jrheum.org
Objective. Multidrug resistance (MDR) transporters may be used as biomarkers to monitor
disease progression in RA and as a predictive tool to establish responsiveness to biological …

A highly precise and portable genome engineering method allows comparison of mutational effects across bacterial species

…, B Bálint, P Bihari, V Lázár, G Apjok… - Proceedings of the …, 2016 - National Acad Sciences
Currently available tools for multiplex bacterial genome engineering are optimized for a few
laboratory model strains, demand extensive prior modification of the host strain, and lead to …

Rapid decline of bacterial drug-resistance in an antibiotic-free environment through phenotypic reversion

…, R Spohn, Z Farkas, V Lazar, Á Györkei, G Apjok… - Elife, 2019 - elifesciences.org
10.7554/eLife.47088.001 Antibiotic resistance typically induces a fitness cost that shapes
the fate of antibiotic-resistant bacterial populations. However, the cost of resistance can be …

Childhood leukaemia in Europe after Chernobyl: 5 year follow-up

…, S Schraub, P Kaatsch, J Michaelis, E Apjok… - British journal of …, 1996 - nature.com
The European Childhood Leukaemia-Lymphoma Incidence Study (ECLIS) is designed to
address concerns about a possible increase in the risk of cancer in Europe following the …

Limited evolutionary conservation of the phenotypic effects of antibiotic resistance mutations

G Apjok, G Boross, Á Nyerges, G Fekete… - Molecular biology …, 2019 - academic.oup.com
Multidrug-resistant clinical isolates are common in certain pathogens, but rare in others.
This pattern may be due to the fact that mutations shaping resistance have species-specific …

[HTML][HTML] Prediction of Therapy Response and Prognosis in Leukemias by Flow Cytometric MDR Assays

J Kappelmayer, Z Hevessy, A Apjok, KT Jakab - EJIFCC, 2013 - ncbi.nlm.nih.gov
Multidrug resistance (MDR) is an unwanted phenomenon, that may cause therapy failure in
several neoplasms including hematological malignancies. The purpose of any type of …

Preparation and characterization of improved gelatin films incorporating hemp and sage oils

AM Cozmuta, A Turila, R Apjok, A Ciocian… - Food …, 2015 - Elsevier
The aim of the study is to prepare and characterize gelatin films incorporating hemp and
sage oil, to obtain an edible film which combines both food preservation and nutritional …

Active packaging based on cellulose-chitosan-Ag/TiO2 nanocomposite for storage of clarified butter

R Apjok, A Mihaly Cozmuta, A Peter, L Mihaly Cozmuta… - Cellulose, 2019 - Springer
Three active cellulose-based papers coated in chitosan (P-CH), chitosan-TiO 2 (P-CH-TiO 2
) and chitosan-Ag/TiO 2 (P-CH-Ag/TiO 2 ), respectively were real-time aged for 6 months at 4…

Immobilization of baker's yeast in the alginate-based hydrogels to impart sensorial characteristics to frozen dough bread

AM Cozmuta, A Jastrzębska, R Apjok, M Petrus… - Food Bioscience, 2021 - Elsevier
The objective of this study was to improve the sensorial characteristics of frozen dough bread
by replacing free yeast cells with calcium alginate-yeast cells (CAY) or calcium alginate–…