User profiles for A. V. RAMANAN

AV Ramanan

University Hospitals Bristol NHS Trust/University of Bristol
Verified email at bristol.ac.uk
Cited by 16413

Recommendations for the management of hemophagocytic lymphohistiocytosis in adults

…, G Lachmann, KE Nichols, AV Ramanan… - Blood, The Journal …, 2019 - ashpublications.org
Hemophagocytic lymphohistiocytosis (HLH) is a severe hyperinflammatory syndrome induced
by aberrantly activated macrophages and cytotoxic T cells. The primary (genetic) form, …

Effect of breast feeding on risk of coeliac disease: a systematic review and meta-analysis of observational studies

AK Akobeng, AV Ramanan, I Buchan… - Archives of disease in …, 2006 - adc.bmj.com
Background: Coeliac disease (CD) is a disorder that may depend on genetic, immunological,
and environmental factors. Recent observational studies suggest that breast feeding may …

[HTML][HTML] A national consensus management pathway for paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS): results of a …

…, E Whittaker, P Ramnarayan, AV Ramanan… - The Lancet Child & …, 2021 - thelancet.com
Paediatric inflammatory multisystem syndrome temporally associated with COVID-19 (PIMS-TS)
is a novel condition that was first reported in April, 2020. We aimed to develop a national …

Efficacy and safety of baricitinib for the treatment of hospitalised adults with COVID-19 (COV-BARRIER): a randomised, double-blind, parallel-group, placebo …

VC Marconi, AV Ramanan, S de Bono… - The lancet Respiratory …, 2021 - thelancet.com
Background Baricitinib is an oral selective Janus kinase 1/2 inhibitor with known anti-inflammatory
properties. This study evaluates the efficacy and safety of baricitinib in combination …

2016 classification criteria for macrophage activation syndrome complicating systemic juvenile idiopathic arthritis: a European League Against Rheumatism/American …

…, J Pachlopnik Schmid, AV Ramanan… - Arthritis & …, 2016 - Wiley Online Library
Ramanan,17 Ricardo Russo,18 Rayfel Schneider,19 Gary Sterba,20 Yosef Uziel,21 Carol
… Kelly A, Ramanan AV. Recognition and management of macrophage activation syndrome …

[HTML][HTML] Efficacy and safety of baricitinib plus standard of care for the treatment of critically ill hospitalised adults with COVID-19 on invasive mechanical ventilation or …

EW Ely, AV Ramanan, CE Kartman… - The Lancet …, 2022 - thelancet.com
Background The oral, selective Janus kinase 1/2 inhibitor baricitinib has shown efficacy in
studies of hospitalised adults with COVID-19. COV-BARRIER (NCT04421027) was a …

[HTML][HTML] Adalimumab plus methotrexate for uveitis in juvenile idiopathic arthritis

AV Ramanan, AD Dick, AP Jones… - … England Journal of …, 2017 - Mass Medical Soc
Background Adalimumab, a fully human anti–tumor necrosis factor α monoclonal antibody,
is effective in the treatment of juvenile idiopathic arthritis (JIA). We tested the efficacy of …

Coronavirus disease 2019 (COVID-19) in children-what we know so far and what we do not

…, NM Rao, A Goenka, M Roderick, AV Ramanan - Indian pediatrics, 2020 - Springer
Pediatric coronavirus disease-19 (COVID-19) infection is relatively mild when compared to
adults, and children are reported to have a better prognosis. Mortality in children appears rare…

[HTML][HTML] Tocilizumab plus standard care versus standard care in patients in India with moderate to severe COVID-19-associated cytokine release syndrome …

…, R Pandit, V Mishra, M Goel, AV Ramanan - The Lancet …, 2021 - thelancet.com
Background Global randomised controlled trials of the anti-IL-6 receptor antibody tocilizumab
in patients admitted to hospital with COVID-19 have shown conflicting results but potential …

The diagnostic significance of soluble CD163 and soluble interleukin‐2 receptor α‐chain in macrophage activation syndrome and untreated new‐onset systemic …

…, DD Sherry, MH Passo, AV Ramanan… - Arthritis & …, 2007 - Wiley Online Library
Objective Macrophage activation syndrome is characterized by an overwhelming inflammatory
reaction driven by excessive expansion of T cells and hemophagocytic macrophages. …