The endothelial generation of reactive oxygen species (ROS) is important both physiologically
and in the pathogenesis of many cardiovascular disorders. ROS generated by endothelial …

Approximately half of the patients with signs and symptoms of heart failure have a left ventricular
ejection fraction that is not markedly abnormal. Despite the historically initial surprise, …

Increased oxidative stress plays an important role in the pathophysiology of cardiovascular
diseases such as hypertension, atherosclerosis, diabetes, cardiac hypertrophy, heart failure, …

Epithelial-mesenchymal transition (EMT) of adherent epithelial cells to a migratory mesenchymal
state has been implicated in tumor metastasis in preclinical models. To investigate its …

Rare circulating tumor cells (CTCs) present in the bloodstream of patients with cancer
provide a potentially accessible source for detection, characterization, and monitoring of …

Background The impact of COVID-19 on physical and mental health and employment after
hospitalisation with acute disease is not well understood. The aim of this study was to …

COVID-19 is a disease with unique characteristics that include lung thrombosis 1 , frequent
diarrhoea 2 , abnormal activation of the inflammatory response 3 and rapid deterioration of …

Circulating tumor cells (CTCs) are shed into the bloodstream from primary and metastatic
tumor deposits. Their isolation and analysis hold great promise for the early detection of …

Background Hereditary transthyretin amyloidosis is caused by pathogenic single-nucleotide
variants in the gene encoding transthyretin (TTR) that induce transthyretin misfolding and …

Background Whether revascularization by percutaneous coronary intervention (PCI) can
improve event-free survival and left ventricular function in patients with severe ischemic left …