Clinical and radiographic outcomes of four different treatment strategies in patients with early rheumatoid arthritis (the BeSt study): a randomized, controlled trial
…, KH Han, ML Westedt, AH Gerards… - Arthritis & …, 2005 - Wiley Online Library
Methods. In a multicenter, randomized clinical trial, 508 patients were allocated to 1 of 4
treatment strategies: sequential disease-modifying antirheumatic drug monotherapy (group 1), …
treatment strategies: sequential disease-modifying antirheumatic drug monotherapy (group 1), …
[HTML][HTML] Role of ultrasonography in diagnosing early rheumatoid arthritis and remission of rheumatoid arthritis-a systematic review of the literature
DF Ten Cate, JJ Luime, N Swen, AH Gerards… - Arthritis research & …, 2013 - Springer
Introduction Ultrasonography (US) might have an added value to clinical examination in
diagnosing early rheumatoid arthritis (RA) and assessing remission of RA. We aimed to clarify …
diagnosing early rheumatoid arthritis (RA) and assessing remission of RA. We aimed to clarify …
Inhibition of cytokine production by methotrexate. Studies in healthy volunteers and patients with rheumatoid arthritis
AH Gerards, S De Lathouder, ER De Groot… - …, 2003 - academic.oup.com
Objectives. To analyse whether the beneficial effects of methotrexate in rheumatoid arthritis (RA)
could be due to inhibition of inflammatory cytokine production. Methods. Cytokine …
could be due to inhibition of inflammatory cytokine production. Methods. Cytokine …
A randomised, double blind, placebo controlled, multicentre trial of combination therapy with methotrexate plus ciclosporin in patients with active psoriatic arthritis
…, Z Karim, R Wakefield, AH Gerards… - Annals of the …, 2005 - ard.bmj.com
Objectives: To evaluate the safety and efficacy of adding ciclosporin A (CSA) to the
treatment of patients with psoriatic arthritis (PsA) demonstrating an incomplete response to …
treatment of patients with psoriatic arthritis (PsA) demonstrating an incomplete response to …
Induction therapy with a combination of DMARDs is better than methotrexate monotherapy: first results of the tREACH trial
…, PA Van Der Lubbe, AH Gerards… - Annals of the …, 2013 - ard.bmj.com
Objective To determine the most effective induction disease-modifying antirheumatic drug (DMARD)
strategy in early rheumatoid arthritis (RA), second to compare one single dose of …
strategy in early rheumatoid arthritis (RA), second to compare one single dose of …
Randomised comparison of initial triple DMARD therapy with methotrexate monotherapy in combination with low-dose glucocorticoid bridging therapy; 1-year data of …
…, PA Van Der Lubbe, AH Gerards… - Annals of the …, 2014 - ard.bmj.com
Objectives To compare 1-year clinical efficacy of (1) initial triple disease-modifying antirheumatic
drug therapy (iTDT) with initial methotrexate (MTX) monotherapy (iMM) and (2) different …
drug therapy (iTDT) with initial methotrexate (MTX) monotherapy (iMM) and (2) different …
[HTML][HTML] Disease flares in rheumatoid arthritis are associated with joint damage progression and disability: 10-year results from the BeSt study
IM Markusse, L Dirven, AH Gerards… - Arthritis research & …, 2015 - Springer
Introduction Flares in patients with rheumatoid arthritis are suggested to sometimes
spontaneously resolve. Targeted therapy could then entail possible overtreatment. We aimed to …
spontaneously resolve. Targeted therapy could then entail possible overtreatment. We aimed to …
Association with joint damage and physical functioning of nine composite indices and the 2011 ACR/EULAR remission criteria in rheumatoid arthritis
…, R Koevoets, D van der Heijde, AH Gerards… - Annals of the …, 2011 - ard.bmj.com
Objective To compare nine disease activity indices and the new American College of
Rheumatology (ACR)/European League against Rheumatism (EULAR) remission criteria in …
Rheumatology (ACR)/European League against Rheumatism (EULAR) remission criteria in …
Methotrexate polyglutamates in erythrocytes are associated with lower disease activity in patients with rheumatoid arthritis
…, AE Weel, AM Huisman, AH Gerards… - Annals of the …, 2015 - ard.bmj.com
Objective To investigate if erythrocyte-methotrexate-polyglutamate (MTX-PG) concentrations
in patients with rheumatoid arthritis (RA) are associated with disease activity or adverse …
in patients with rheumatoid arthritis (RA) are associated with disease activity or adverse …
Limited efficacy of conventional DMARDs after initial methotrexate failure in patients with recent onset rheumatoid arthritis treated according to the disease activity …
…, D van Zeben, PJSM Kerstens, AH Gerards… - Annals of the …, 2007 - ard.bmj.com
Objectives: To determine the efficacy of subsequent disease modifying antirheumatic drug (DMARD)
therapies after initial methotrexate (MTX) failure in patients with recent onset …
therapies after initial methotrexate (MTX) failure in patients with recent onset …