Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis

…, B Drexel, R Seger, T Kusuma, AF Jansson… - Journal of Experimental …, 2011 - rupress.org
Chronic mucocutaneous candidiasis disease (CMCD) may be caused by autosomal dominant
(AD) IL-17F deficiency or autosomal recessive (AR) IL-17RA deficiency. Here, using whole…

[HTML][HTML] Consensus protocols for the diagnosis and management of the hereditary autoinflammatory syndromes CAPS, TRAPS and MKD/HIDS: a German PRO-KIND …

…, G Horneff, D Holzinger, N Rieber, AF Jansson… - Pediatric …, 2020 - Springer
Background Rare autoinflammatory diseases (AIDs) including Cryopyrin-Associated Periodic
Syndrome (CAPS), Tumor Necrosis Receptor-Associated Periodic Syndrome (TRAPS) and …

Novel signal transducer and activator of transcription 3 (STAT3) mutations, reduced TH17 cell numbers, and variably defective STAT3 phosphorylation in hyper-IgE …

…, J Reichenbach, JC Carey, Q Zhu, AF Jansson… - Journal of Allergy and …, 2008 - Elsevier
BACKGROUND: Hyper-IgE syndrome (HIES) is a rare, autosomal-dominant immunodeficiency
characterized by eczema, Staphylococcus aureus skin abscesses, pneumonia with …

Clinical score for nonbacterial osteitis in children and adults

AF Jansson, TH Müller, L Gliera… - … : Official Journal of …, 2009 - Wiley Online Library
… diagnosed according to the clinical criteria proposed by Jansson et al (13). Data retrieved
included … Jansson had full access to all of the data in the study and takes responsibility for the …

Diagnostic approach to the hyper-IgE syndromes: immunologic and clinical key findings to differentiate hyper-IgE syndromes from atopic dermatitis

…, V Wahn, M Hoenig, AF Jansson… - Journal of allergy and …, 2010 - Elsevier
BACKGROUND: Hyper-IgE syndromes (HIES) are primary immunodeficiency disorders
characterized by Staphylococcus aureus abscesses, recurrent pneumonia, increased serum IgE …

Nonbacterial osteitis in children: data of a German Incidence Surveillance Study

AF Jansson, V Grote, ESPED Study Group - Acta paediatrica, 2011 - Wiley Online Library
Aim: To analyse the incidence, clinical presentation, laboratory and radiological findings, as
well as diagnostic approaches and therapeutic procedures in paediatric patients suffering …

Whole-body magnetic resonance imaging in chronic recurrent multifocal osteomyelitis: clinical longterm assessment may underestimate activity

…, MF Reiser, S Weckbach, AF Jansson - The Journal of …, 2015 - jrheum.org
Objective. (1) To examine how many patients have clinically and/or radiologically active chronic
recurrent multifocal osteomyelitis (CRMO) ≥ 10 years after first onset of symptoms, and (…

[HTML][HTML] Practice and consensus-based strategies in diagnosing and managing systemic juvenile idiopathic arthritis in Germany

…, T Kallinich, N Rieber, M Hufnagel, AF Jansson… - Pediatric …, 2018 - Springer
Background Systemic juvenile idiopathic arthritis (SJIA) is an autoinflammatory disease
associated with chronic arthritis. Early diagnosis and effective therapy of SJIA is desirable, so …

Whole-body MRI in patients with non-bacterial osteitis: radiological findings and correlation with clinical data

…, LL Geyer, AM Voit, F Bleisteiner, AF Jansson… - European …, 2017 - Springer
Objectives To correlate clinical findings of Non-bacterial Osteitis (NBO) with whole-body
MRI (WB-MRI) findings and determine a radiologic index for NBO (RINBO) which allows …

Development of the autoinflammatory disease damage index (ADDI)

…, HM Hoffman, A Insalaco, AF Jansson… - Annals of the …, 2017 - ard.bmj.com
Objectives Autoinflammatory diseases cause systemic inflammation that can result in damage
to multiple organs. A validated instrument is essential to quantify damage in individual …