Clinical trial results provide the critical evidence base for evaluating the safety and efficacy
of new medicines and medical products. Efficacy and safety may differ among population …

ContextOsteoarthritis (OA) is often treated with nonsteroidal anti-inflammatory drugs (NSAIDs),
acetaminophen, or specific inhibitors of cyclooxygenase 2 (COX-2).ObjectiveTo assess …

Background Odanacatib, a cathepsin K inhibitor, reduces bone resorption while maintaining
bone formation. Previous work has shown that odanacatib increases bone mineral density …

Nicotinic acid (niacin) induces beneficial changes in serum lipoproteins and has been
associated with beneficial cardiovascular effects. Niacin reduces low-density lipoprotein, …

… In their recent letter to the editor, Braunstein and Polis address … The 2003 article by Lisse
and colleagues (including Polis) … In their Annals letter, Braunstein and Polis say that Merck's …

To aid clinicians in selecting the appropriate approach for treating patients with diabetic foot
infections, we investigated whether any baseline clinical findings predicted an unfavourable …

The purpose of the study was to assess in patients with a diabetic foot infection (DFI), whether
differences in skin temperature of the affected foot as compared to the corresponding site …

Objective: Evaluate the lipid-altering effects of ezetimibe added to ongoing statin therapy,
statin titration, switching from statin monotherapy to a more potent statin or to ezetimibe/…

Patients with the metabolic syndrome are at an increased risk of cardiovascular disease
and might require intensive lipid therapy. Many patients remain at the starting dose of lipid …

Scoring the severity of a diabetic foot wound infection may help assess the severity, determine
the type and urgency of antibiotic and surgical treatment needed, and predict clinical …