Reproducibility of joint swelling assessments in long-lasting rheumatoid arthritis: influence on Disease Activity Score-28 values (SEA-Repro study part I)

…, G Chalès, L Grange, C Hacquard… - The Journal of …, 2010 - jrheum.org
Objectives. To evaluate the reproducibility of clinical synovitis assessments in rheumatoid
arthritis and the effect of variability on the Disease Activity Score-28 (DAS28). Methods. Seven …

Reproducibility of joint swelling assessment by sonography in patients with long-lasting rheumatoid arthritis (SEA-Repro study part II)

…, C Hudry, G Chalès, L Grange, C Hacquard… - The Journal of …, 2010 - jrheum.org
Objective. To evaluate the intraobserver and interobserver reproducibility of B-mode and
power Doppler (PD) sonography in patients with active long-standing rheumatoid arthritis (RA) …

Assessment of peripheral enthesitis in the spondylarthropathies by ultrasonography combined with power Doppler: a cross‐sectional study

…, R Said‐Nahal, C Hacquard‐Bouder… - Arthritis & …, 2003 - Wiley Online Library
Objective To assess the prevalence and severity of peripheral enthesitis among the different
subtypes of spondylarthropathy (SpA) by using ultrasonography (US) in B mode with power …

Defective costimulatory function is a striking feature of antigen‐presenting cells in an HLA–B27–transgenic rat model of spondylarthropathy

C Hacquard‐Bouder, G Falgarone… - Arthritis & …, 2004 - Wiley Online Library
Objective A disease resembling the human spondylarthropathies develops in HLA–B27–transgenic
rats. This disease in rats is mediated by CD4+ T cells, but antigen‐presenting cells (…

HLA-B27 heavy chain homodimers are expressed in HLA-B27 transgenic rodent models of spondyloarthritis and are ligands for paired Ig-like receptors

…, LA Bird, M Roddis, C Hacquard-Bouder… - The Journal of …, 2004 - journals.aai.org
HLA-B27 transgenic rats and strains of HLA-B27-transgenic β 2-microglobulin (β 2 m)-deficient
mice develop a multisystem inflammatory disease affecting the joints, skin, and bowel …

Alteration of antigen‐independent immunologic synapse formation between dendritic cells from HLA–B27–transgenic rats and CD4+ T cells: selective impairment of …

C Hacquard‐Bouder, MS Chimenti… - Arthritis & …, 2007 - Wiley Online Library
Objective To investigate the molecular mechanism responsible for the reduced capacity of
dendritic cells (DCs) from HLA–B27–transgenic rats to form conjugates with naive T cells. …

Dendritic cells from spondylarthritis‐prone HLA–B27–transgenic rats display altered cytoskeletal dynamics, class II major histocompatibility complex expression, and …

…, E Donnadieu, C Hacquard‐Bouder… - Arthritis & …, 2009 - Wiley Online Library
Objective Spondylarthritis (SpA) is characterized by spinal and peripheral joint inflammation,
frequently combined with extraarticular manifestations. Despite the well‐established …

Animal models of HLA-B27-associated diseases: new outcomes

C Hacquard-Bouder, M Ittah, M Breban - Joint Bone Spine, 2006 - Elsevier
The HLA-B27 molecule is strongly associated with the spondyloarthropathies, a group of
chronic inflammatory diseases, affecting the skeleton, the bowel and the skin. This association …

Factors influencing concordance between clinical and ultrasound findings in rheumatoid arthritis

…, G Chales, L Grange, C Hacquard-Bouder… - The Journal of …, 2013 - jrheum.org
Objective. Clinical joint examination (CJE) is less time-consuming than ultrasound (US) in
rheumatoid arthritis (RA). Low concordance between CJE and US would indicate that the 2 …

Animal models of HLA-B27-associated diseases

M Breban, C Hacquard-Bouder… - Current molecular …, 2004 - ingentaconnect.com
The HLA-B27 molecule is strongly associated with the spondyloarthropathies (SpA), a
group of inflammatory conditions affecting the skeleton, the skin and several mucosae. The …