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Diacerein inhibits the synthesis of resorptive enzymes and reduces osteoclastic differentiation/survival in osteoarthritic subchondral bone: a possible mechanism for a protective effect against subchondral bone remodelling.
Boileau C, Tat SK, Pelletier JP, Cheng S, Martel-Pelletier J. Boileau C, et al. Among authors: tat sk. Arthritis Res Ther. 2008;10(3):R71. doi: 10.1186/ar2444. Epub 2008 Jun 25. Arthritis Res Ther. 2008. PMID: 18578867 Free PMC article.