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Year Number of Results
1979 2
1981 1
1997 1
1998 2
1999 1
2000 2
2001 5
2002 1
2003 6
2004 5
2005 6
2006 4
2007 8
2008 7
2009 3
2010 3
2011 8
2012 4
2013 6
2014 6
2015 12
2016 11
2017 21
2018 8
2019 7
2020 9
2021 8
2022 14
2023 10
2024 2

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165 results

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Page 1
Preclinical Characterization of AZD5305, A Next-Generation, Highly Selective PARP1 Inhibitor and Trapper.
Illuzzi G, Staniszewska AD, Gill SJ, Pike A, McWilliams L, Critchlow SE, Cronin A, Fawell S, Hawthorne G, Jamal K, Johannes J, Leonard E, Macdonald R, Maglennon G, Nikkilä J, O'Connor MJ, Smith A, Southgate H, Wilson J, Yates J, Cosulich S, Leo E. Illuzzi G, et al. Among authors: mcwilliams l. Clin Cancer Res. 2022 Nov 1;28(21):4724-4736. doi: 10.1158/1078-0432.CCR-22-0301. Clin Cancer Res. 2022. PMID: 35929986 Free PMC article.
Preclinical Characterization of AZD9574, a Blood-Brain Barrier Penetrant Inhibitor of PARP1.
Staniszewska AD, Pilger D, Gill SJ, Jamal K, Bohin N, Guzzetti S, Gordon J, Hamm G, Mundin G, Illuzzi G, Pike A, McWilliams L, Maglennon G, Rose J, Hawthorne G, Cortes Gonzalez M, Halldin C, Johnström P, Schou M, Critchlow SE, Fawell S, Johannes JW, Leo E, Davies BR, Cosulich S, Sarkaria JN, O'Connor MJ, Hamerlik P. Staniszewska AD, et al. Among authors: mcwilliams l. Clin Cancer Res. 2024 Apr 1;30(7):1338-1351. doi: 10.1158/1078-0432.CCR-23-2094. Clin Cancer Res. 2024. PMID: 37967136
Discovery of 5-{4-[(7-Ethyl-6-oxo-5,6-dihydro-1,5-naphthyridin-3-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD5305): A PARP1-DNA Trapper with High Selectivity for PARP1 over PARP2 and Other PARPs.
Johannes JW, Balazs A, Barratt D, Bista M, Chuba MD, Cosulich S, Critchlow SE, Degorce SL, Di Fruscia P, Edmondson SD, Embrey K, Fawell S, Ghosh A, Gill SJ, Gunnarsson A, Hande SM, Heightman TD, Hemsley P, Illuzzi G, Lane J, Larner C, Leo E, Liu L, Madin A, Martin S, McWilliams L, O'Connor MJ, Orme JP, Pachl F, Packer MJ, Pei X, Pike A, Schimpl M, She H, Staniszewska AD, Talbot V, Underwood E, Varnes JG, Xue L, Yao T, Zhang K, Zhang AX, Zheng X. Johannes JW, et al. Among authors: mcwilliams l. J Med Chem. 2021 Oct 14;64(19):14498-14512. doi: 10.1021/acs.jmedchem.1c01012. Epub 2021 Sep 27. J Med Chem. 2021. PMID: 34570508
Direct activation of KCC2 arrests benzodiazepine refractory status epilepticus and limits the subsequent neuronal injury in mice.
Jarvis R, Josephine Ng SF, Nathanson AJ, Cardarelli RA, Abiraman K, Wade F, Evans-Strong A, Fernandez-Campa MP, Deeb TZ, Smalley JL, Jamier T, Gurrell IK, McWilliams L, Kawatkar A, Conway LC, Wang Q, Burli RW, Brandon NJ, Chessell IP, Goldman AJ, Maguire JL, Moss SJ. Jarvis R, et al. Among authors: mcwilliams l. Cell Rep Med. 2023 Mar 21;4(3):100957. doi: 10.1016/j.xcrm.2023.100957. Epub 2023 Mar 7. Cell Rep Med. 2023. PMID: 36889319 Free PMC article.
Exercise Interventions for Women with Ovarian Cancer: A Realist Review.
McGrath D, O'Halloran P, Prue G, Brown M, Millar J, O'Donnell A, McWilliams L, Murphy C, Hinds G, Reid J. McGrath D, et al. Among authors: mcwilliams l. Healthcare (Basel). 2022 Apr 13;10(4):720. doi: 10.3390/healthcare10040720. Healthcare (Basel). 2022. PMID: 35455897 Free PMC article. Review.
An accent modification program.
Freysteinson WM, Adams JD, Cesario S, Belay HA, Clutter P, Du J, Duson BM, Goff M, McWilliams L, Nurse RP, Allam Z. Freysteinson WM, et al. Among authors: mcwilliams l. J Prof Nurs. 2017 Jul-Aug;33(4):299-304. doi: 10.1016/j.profnurs.2016.11.003. Epub 2016 Nov 17. J Prof Nurs. 2017. PMID: 28734491 No abstract available.
Techniques to Enable 1536-Well Phenotypic Screening.
Knight S, Plant H, McWilliams L, Wigglesworth M. Knight S, et al. Among authors: mcwilliams l. Methods Mol Biol. 2018;1787:263-278. doi: 10.1007/978-1-4939-7847-2_20. Methods Mol Biol. 2018. PMID: 29736725
165 results