Jaw claudication in primary amyloidosis: unusual presentation of a rare disease

Christopher H Churchill; Andy Abril; Murli Krishna; Mark L Callman; William W Ginsburg

Jaw claudication in primary amyloidosis: unusual presentation of a rare disease

J Rheumatol. 2003 Oct;30(10):2283-6.

Authors

Christopher H Churchill¹, Andy Abril, Murli Krishna, Mark L Callman, William W Ginsburg

Affiliation

¹ Division of Rheumatology, Mayo Clinic Jacksonville, 4500 San Pablo Road, Jacksonville, FL 32224, USA.

PMID: 14528530

Abstract

We describe two patients with temporal artery biopsy-proven amyloidosis presenting with symptoms of jaw claudication, visual disturbance, and proximal muscle stiffness suggestive of giant cell arteritis (GCA) and polymyalgia rheumatica. At the onset of disease, neither patient had other characteristic symptoms to suggest primary amyloid. We point out similarities between GCA and primary amyloid that can lead to confusion in diagnosis.

Publication types

Case Reports

MeSH terms

Aged
Amyloid / analysis
Amyloid / metabolism
Amyloidosis / complications
Amyloidosis / pathology*
Coloring Agents / chemistry
Coloring Agents / metabolism
Congo Red / chemistry
Congo Red / metabolism
Diagnosis, Differential
Giant Cell Arteritis / pathology
Humans
Jaw Diseases / etiology
Jaw Diseases / pathology*
Male
Middle Aged
Muscle Weakness / etiology
Muscle Weakness / pathology*
Polymyalgia Rheumatica / pathology
Temporal Arteries / metabolism
Temporal Arteries / pathology*

Substances

Amyloid
Coloring Agents
Congo Red