Umbilical artery blood flow velocity in pregnancies complicated by systemic lupus erythematosus

J Clin Ultrasound. 1998 Oct;26(8):379-82. doi: 10.1002/(sici)1097-0096(199810)26:8<379::aid-jcu1>3.0.co;2-f.

Abstract

Purpose: We evaluated the role of umbilical artery Doppler velocimetry in the surveillance of pregnancies complicated by systemic lupus erythematosus (SLE).

Methods: We retrospectively studied 56 women with SLE whose pregnancies were managed at our perinatal center between 1988 and 1995.

Results: Absent or reversed end-diastolic flow velocity was detected in 6 (11%) of 56 patients. This sub-group of patients had an increased risk of pre-eclampsia, intrauterine growth restriction, cesarean section, and preterm delivery.

Conclusions: A high incidence (11%) of abnormal umbilical artery waveforms was detected. This finding was associated with an increased risk of maternal and fetal complications.

MeSH terms

  • Adult
  • Blood Flow Velocity
  • Chi-Square Distribution
  • Confidence Intervals
  • Female
  • Humans
  • Laser-Doppler Flowmetry
  • Lupus Erythematosus, Systemic / physiopathology*
  • Odds Ratio
  • Pregnancy
  • Pregnancy Complications / physiopathology*
  • Retrospective Studies
  • Statistics, Nonparametric
  • Ultrasonography, Prenatal*
  • Umbilical Arteries / diagnostic imaging*
  • Umbilical Arteries / physiopathology