Abstract
This report describes a case of a female with systemic lupus erythematosus, who was subsequently diagnosed with Fabry's disease. Due to similarities in the organs involved by these two multisystem disorders, difficulties were encountered in establishing a prompt diagnosis of Fabry's disease. That and subsequent management of this patient are discussed. A literature review of the coexistence of the two disorders along with the potential pathogenic mechanisms explaining this association are explored.
Publication types
-
Case Reports
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Endocardium / ultrastructure
-
Fabry Disease / complications*
-
Fabry Disease / metabolism
-
Fabry Disease / pathology
-
Female
-
Glycosphingolipids / urine
-
Humans
-
Lupus Erythematosus, Systemic / complications*
-
Lupus Erythematosus, Systemic / metabolism
-
Lupus Erythematosus, Systemic / pathology
-
Lysosomes / metabolism
-
Lysosomes / ultrastructure
-
Middle Aged
-
Myocardium / ultrastructure
-
alpha-Galactosidase / metabolism
Substances
-
Glycosphingolipids
-
ceramide trihexoside
-
alpha-Galactosidase