Effect of thyroid hormone treatment on thyromegaly in children and adolescents with Hashimoto disease

J Pediatr. 1994 Apr;124(4):599-601. doi: 10.1016/s0022-3476(05)83141-5.

Abstract

The effect of thyroid hormone treatment on thyromegaly was evaluated in 69 patients < or = 18 years of age with goitrous Hashimoto disease. Changes in goiter size were related to pretreatment thyroid function (serum thyroxine and thyrotropin concentrations). We found that only hypothyroid patients had a clear diminution of their thyromegaly when given thyroid hormone.

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Female
  • Goiter / blood
  • Goiter / drug therapy*
  • Goiter / etiology
  • Humans
  • Hypothyroidism / drug therapy
  • Hypothyroidism / etiology
  • Male
  • Retrospective Studies
  • Thyroid Hormones / therapeutic use*
  • Thyroiditis, Autoimmune / blood
  • Thyroiditis, Autoimmune / complications
  • Thyroiditis, Autoimmune / drug therapy*
  • Thyrotropin / blood
  • Thyroxine / blood

Substances

  • Thyroid Hormones
  • Thyrotropin
  • Thyroxine