Cardiac involvement in polymyositis: a clinicopathologic study of 20 autopsied patients

Arthritis Rheum. 1979 Oct;22(10):1088-92. doi: 10.1002/art.1780221007.

Abstract

Cardiac involvement in polymyositis was investigated in 20 autopsied cases. Clinically, 13 of 18 patients had abnormal electrocardiograms, and 9 of the 20 patients had previous evidence of congestive heart failure. Histologically documented myocarditis was detected in 6 patients (4 with congestive heart failure and 2 without), 4 of whom also had small vessel disease of the myocardium. Patients with polymyositis may have a cardiopathy in the absence of overt myocardial inflammatory disease.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child, Preschool
  • Coronary Vessels / pathology*
  • Dermatomyositis / diagnosis
  • Dermatomyositis / pathology*
  • Dermatomyositis / physiopathology
  • Electrocardiography
  • Female
  • Humans
  • Lung Diseases / diagnostic imaging
  • Lung Diseases / pathology
  • Male
  • Middle Aged
  • Myocarditis / diagnosis
  • Myocarditis / pathology*
  • Myocarditis / physiopathology
  • Myocardium / pathology*
  • Organ Size
  • Radiography
  • Time Factors