Current concepts in the treatment of gouty arthritis

Orthop Surg. 2013 Feb;5(1):6-12. doi: 10.1111/os.12024.

Abstract

Gouty arthritis is an extremely painful condition that causes functional impairment. Gouty arthritis has become increasingly complex because of multiple comorbidities, iatrogenic factors and hyperuricemia that is refractory to treatment. In this review, we present a general overview of gouty arthritis including its pathophysiology, clinical presentations, diagnosis, predisposing factors and prophylactic therapy for preventing gouty arthritis flares.

Publication types

  • Review

MeSH terms

  • Adrenal Cortex Hormones / therapeutic use
  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use
  • Arthritis, Gouty / diagnosis
  • Arthritis, Gouty / drug therapy*
  • Arthritis, Gouty / surgery
  • Colchicine / therapeutic use
  • Gout Suppressants / therapeutic use
  • Humans
  • Interleukin-1beta / antagonists & inhibitors
  • Risk Reduction Behavior
  • Uric Acid / metabolism

Substances

  • Adrenal Cortex Hormones
  • Anti-Inflammatory Agents, Non-Steroidal
  • Gout Suppressants
  • Interleukin-1beta
  • Uric Acid
  • Colchicine