Autoinflammatory disease reloaded: a clinical perspective

Daniel L Kastner; Ivona Aksentijevich; Raphaela Goldbach-Mansky

doi:10.1016/j.cell.2010.03.002

Autoinflammatory disease reloaded: a clinical perspective

Cell. 2010 Mar 19;140(6):784-90. doi: 10.1016/j.cell.2010.03.002.

Authors

Daniel L Kastner¹, Ivona Aksentijevich, Raphaela Goldbach-Mansky

Affiliation

¹ Laboratory of Clinical Investigation, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA. kastnerd@mail.nih.gov

Abstract

Our understanding of the etiology of autoinflammatory disease is growing rapidly. Recent advances offer new opportunities for therapeutic intervention and suggest that the definition of what constitutes an autoinflammatory disease should be reassessed.

Publication types

Research Support, N.I.H., Intramural

MeSH terms

Animals
Autoantibodies
Autoimmune Diseases / immunology
Cytokines / immunology
Hereditary Autoinflammatory Diseases / drug therapy
Hereditary Autoinflammatory Diseases / immunology*
Hereditary Autoinflammatory Diseases / physiopathology
Humans

Substances

Autoantibodies
Cytokines

Abstract

Publication types

MeSH terms

Substances

Grants and funding