[18F]fluorodeoxyglucose positron emission tomography is a useful tool to diagnose the early stage of Takayasu's arteritis and to evaluate the activity of the disease

Mod Rheumatol. 2006;16(4):243-7. doi: 10.1007/s10165-006-0485-3.

Abstract

Takayasu's arteritis (TA) is a rare disease that can be difficult to diagnose in its early stage. A young woman with a fever and neck pain was thought to have TA, although computed tomographic angiography did not show any specific changes of the arteries. [(18)F]fluorodeoxyglucose positron emission tomography ([(18)F]FDG-PET) was performed to detect the source of the inflammation. Specific accumulation of [(18)F]FDG-6-phosphate in the thoracic aorta and its direct branches was observed, leading to a diagnosis of TA. [(18)F]FDG-PET is therefore considered to be useful for the diagnosis of early-stage TA.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Coronary Angiography
  • Early Diagnosis
  • Female
  • Fever of Unknown Origin / diagnostic imaging
  • Fever of Unknown Origin / physiopathology
  • Fluorodeoxyglucose F18
  • Humans
  • Positron-Emission Tomography / methods*
  • Radiopharmaceuticals
  • Severity of Illness Index
  • Subclavian Artery / diagnostic imaging
  • Takayasu Arteritis / diagnostic imaging*
  • Takayasu Arteritis / physiopathology*
  • Tomography, X-Ray Computed

Substances

  • Radiopharmaceuticals
  • Fluorodeoxyglucose F18