A case of severe acute pancreatitis, in overlap syndrome of systemic sclerosis and systemic lupus erythematosus, successfully treated with plasmapheresis

Yukie Suzuki; Hiroshi Okamoto; Kyoko Koizumi; Mutsuto Tateishi; Masako Hara; Naoyuki Kamatani

doi:10.1007/s10165-006-0476-4

A case of severe acute pancreatitis, in overlap syndrome of systemic sclerosis and systemic lupus erythematosus, successfully treated with plasmapheresis

Mod Rheumatol. 2006;16(3):172-5. doi: 10.1007/s10165-006-0476-4.

Authors

Yukie Suzuki¹, Hiroshi Okamoto, Kyoko Koizumi, Mutsuto Tateishi, Masako Hara, Naoyuki Kamatani

Affiliation

¹ Institute of Rheumatology, Tokyo Women's Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo, 162-0054, Japan.

PMID: 16767557
DOI: 10.1007/s10165-006-0476-4

Abstract

Here, we describe a case of severe pancreatitis in overlap syndrome of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) in an adult female patient. Treatment with plasmapheresis and high-dose prednisone successfully saved her life and led to remission of the pancreatitis. This is the first case report of severe acute pancreatitis in the setting of overlap syndrome of SLE and SSc. The advantages and disadvantages of the use of corticosteroids are discussed.

Publication types

Case Reports

MeSH terms

Adult
Anti-Inflammatory Agents / administration & dosage*
Anti-Inflammatory Agents / adverse effects
Female
Gabexate / administration & dosage
Humans
Lupus Erythematosus, Systemic / complications*
Methylprednisolone / administration & dosage
Methylprednisolone / adverse effects
Pancreatitis* / etiology
Pancreatitis* / therapy
Plasmapheresis / methods*
Prednisone / administration & dosage
Prednisone / adverse effects
Scleroderma, Systemic / complications*
Serine Proteinase Inhibitors / administration & dosage
Syndrome

Substances

Anti-Inflammatory Agents
Serine Proteinase Inhibitors
Gabexate
Prednisone
Methylprednisolone