[Cryptococcal meningitis disclosed by visual loss in HIV negative patient with ventriculo-atrial shunting]

X Gibold; A Husson; V Corbain; M Vidal; F Gourdon; H Laurichesse; J Beytout; P Irthum; A Ferrier; O Lesens

doi:10.1016/j.revmed.2005.12.004

[Cryptococcal meningitis disclosed by visual loss in HIV negative patient with ventriculo-atrial shunting]

Rev Med Interne. 2006 Apr;27(4):330-2. doi: 10.1016/j.revmed.2005.12.004. Epub 2006 Jan 6.

[Article in French]

Authors

X Gibold¹, A Husson, V Corbain, M Vidal, F Gourdon, H Laurichesse, J Beytout, P Irthum, A Ferrier, O Lesens

Affiliation

¹ Service des Maladies Infectieuses et Tropicales, Hôtel-Dieu, CHU, 63000 Clermont-Ferrand, France.

PMID: 16426708
DOI: 10.1016/j.revmed.2005.12.004

Abstract

Introduction: HIV infection is the main cause of cryptococcal neuromeningitis but other diseases may be associated with this infection.

Case report: We report a case of cryptococcal neuromeningitis in a patient with sarcoidosis and ventriculoatrial shunting. The patient was successfully treated by effective therapy without device withdrawal.

Conclusion: The relationship between cryptococcosis and sarcoïdosis has been already described and may be not fortuitous. However it remains a very rare complication of sarcoidosis. Because of its potential severity (mortality rate of 40%), the diagnosis of cryptococcosis should be evoked as a differential diagnosis of neuro-sarcoidosis.

Publication types

Case Reports
Comparative Study
English Abstract

MeSH terms

Amphotericin B / administration & dosage
Amphotericin B / therapeutic use
Anti-Inflammatory Agents / administration & dosage
Anti-Inflammatory Agents / therapeutic use
Antifungal Agents / administration & dosage
Antifungal Agents / therapeutic use
Blindness / etiology*
Cerebrospinal Fluid Shunts / methods*
Diagnosis, Differential
Drug Therapy, Combination
Eye Infections, Fungal / complications*
Fluconazole / administration & dosage
Fluconazole / therapeutic use
Flucytosine / administration & dosage
Flucytosine / therapeutic use
Fludrocortisone / administration & dosage
Fludrocortisone / therapeutic use
Follow-Up Studies
HIV Seronegativity
Humans
Hydrocephalus / complications
Hydrocephalus / therapy
Hydrocortisone / administration & dosage
Hydrocortisone / therapeutic use
Male
Meningitis, Cryptococcal / diagnosis*
Meningitis, Cryptococcal / drug therapy
Middle Aged
Prednisolone / administration & dosage
Prednisolone / therapeutic use
Sarcoidosis / cerebrospinal fluid
Sarcoidosis / complications*
Sarcoidosis / diagnosis
Sarcoidosis / drug therapy
Time Factors
Treatment Outcome

Substances

Anti-Inflammatory Agents
Antifungal Agents
Amphotericin B
Fluconazole
Prednisolone
Flucytosine
Fludrocortisone
Hydrocortisone