Pediatric-onset mixed connective tissue disease

Richard J Mier; Michael Shishov; Gloria C Higgins; Robert M Rennebohm; Dorothy W Wortmann; Rita Jerath; Ekhlas Alhumoud

doi:10.1016/j.rdc.2005.04.002

Pediatric-onset mixed connective tissue disease

Rheum Dis Clin North Am. 2005 Aug;31(3):483-96, vii. doi: 10.1016/j.rdc.2005.04.002.

Authors

Richard J Mier¹, Michael Shishov, Gloria C Higgins, Robert M Rennebohm, Dorothy W Wortmann, Rita Jerath, Ekhlas Alhumoud

Affiliation

¹ Shriners Hospital for Children, 1900 Richmond Road, Lexington, KY 40502, USA. rmier@shrinenet.org

PMID: 16084320
DOI: 10.1016/j.rdc.2005.04.002

Abstract

This article discusses the literature on pediatric-onset mixed connective tissue disease (MCTD) and adds 34 new cases. Although not benign, pediatric-onset MCTD carries less mortality than adult-onset disease.

Publication types

Review

MeSH terms

Age of Onset
Antibodies / blood
Child
Child, Preschool
Female
Humans
Male
Mixed Connective Tissue Disease* / diagnosis
Mixed Connective Tissue Disease* / epidemiology
Mixed Connective Tissue Disease* / etiology
Prognosis
Ribonucleoproteins / immunology

Substances

Antibodies
Ribonucleoproteins