Effect of joint injections in children with juvenile idiopathic arthritis: evaluation by 3D-gait analysis

Acta Paediatr. 2004 Jul;93(7):906-10.

Abstract

Aim: To investigate how gait patterns change after intra-articular corticosteroid injections (ICIs) in the lower extremities.

Methods: Eighteen children, aged 5-16 y, with juvenile idiopathic arthritis (JIA) and lower extremity involvement participated in the study. Sixty-four joints in the lower extremities were treated with ICIs. The Visual Analogue Scale (VAS, 0-100 mm) was used to assess pain. A 3D motion analysis system and two force plates were used to measure gait parameters, kinematics and kinetics. The first gait analysis was performed before treatment with ICIs, and a second one was done 8-17 d after treatment.

Results: The participants' average rating of pain decreased from 26 mm on the VAS before ICI to 11 mm (p = 0.001) after treatment. The self-chosen walking velocity was significantly faster (p = 0.02) after treatment. The range of knee and ankle joint angles during gait increased significantly (p = 0.03 and 0.04) after treatment. At loading response, the hip extension moment increased (p = 0.01) as did knee flexion moment, and plantar flexion moment at pre-swing increased significantly (p = 0.02 and 0.002) after treatment. The ankle also generated more power (p = 0.005) after treatment.

Conclusion: The study shows positive effects of treatment with ICIs in the lower extremities--especially regarding pain, walking velocity and joint moments. The data indicate that ICI treatment influences the gait pattern also in joints that have not been injected.

Publication types

  • Clinical Trial
  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Ankle / physiopathology
  • Anti-Inflammatory Agents / administration & dosage
  • Anti-Inflammatory Agents / therapeutic use*
  • Arthritis, Juvenile / drug therapy*
  • Biomechanical Phenomena
  • Child
  • Child, Preschool
  • Female
  • Gait / drug effects
  • Gait / physiology*
  • Humans
  • Injections
  • Joints / drug effects
  • Joints / physiopathology
  • Knee / physiopathology
  • Male
  • Methylprednisolone / administration & dosage
  • Methylprednisolone / therapeutic use*
  • Pain / drug therapy
  • Treatment Outcome

Substances

  • Anti-Inflammatory Agents
  • Methylprednisolone