Internal Medicine
Online ISSN : 1349-7235
Print ISSN : 0918-2918
ISSN-L : 0918-2918
CASE REPORTS
A Patient with Takayasu's Arteritis and Rheumatoid Arthritis Who Responded to Tacrolimus Hydrate
Isamu YokoeHitomi HaraokaHideaki Harashima
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JOURNAL OPEN ACCESS

2007 Volume 46 Issue 22 Pages 1873-1877

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Abstract

We encountered the rare case of a 50-year-old woman who developed rheumatoid arthritis (RA) while suffering from Takayasu's arteritis of arch vessel type. prednisolone (PSL) therapy was continued at a maintenance dose of 7.5 mg due to recurring inflammation. She was affected with RA for 7 years after Takayasu's arteritis. Disease-modifying antirheumatic drugs (DMARDs) were unusable because of side effects. In the summer of 2005, RA activity increased, and treatment with tacrolimus hydrate at 1.5 mg was started; thereafter, the activity of RA and Takayasu's arteritis was relieved, especially MRA findings. We report that therapy with tacrolimus hydrate markedly relieved two disorders, and review the literature.

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© 2007 by The Japanese Society of Internal Medicine
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