Molecular Cloning of Monkey Histamine H4 Receptor

Tamaki Oda; Shun-ichiro Matsumoto; Mitsuyuki Matsumoto; Jun Takasaki; Masazumi Kamohara; Takatoshi Soga; Hideki Hiyama; Masato Kobori; Masao Katoh

doi:10.1254/jphs.SC0050033

Short Communications

Molecular Cloning of Monkey Histamine H₄ Receptor

Tamaki Oda, Shun-ichiro Matsumoto, Mitsuyuki Matsumoto, Jun Takasaki, Masazumi Kamohara, Takatoshi Soga, Hideki Hiyama, Masato Kobori, Masao Katoh

Author information

Tamaki Oda
Molecular Medicine Laboratories, Yamanouchi Pharmaceutical Co., Ltd.
Shun-ichiro Matsumoto
Molecular Medicine Laboratories, Yamanouchi Pharmaceutical Co., Ltd.
Mitsuyuki Matsumoto
Molecular Medicine Laboratories, Yamanouchi Pharmaceutical Co., Ltd.
Jun Takasaki
Molecular Medicine Laboratories, Yamanouchi Pharmaceutical Co., Ltd.
Masazumi Kamohara
Molecular Medicine Laboratories, Yamanouchi Pharmaceutical Co., Ltd.
Takatoshi Soga
Molecular Medicine Laboratories, Yamanouchi Pharmaceutical Co., Ltd.
Hideki Hiyama
Molecular Medicine Laboratories, Yamanouchi Pharmaceutical Co., Ltd.
Masato Kobori
Molecular Medicine Laboratories, Yamanouchi Pharmaceutical Co., Ltd.
Masao Katoh
Molecular Medicine Laboratories, Yamanouchi Pharmaceutical Co., Ltd.

Keywords: histamine, H₄ receptor, G-protein coupled receptor

JOURNAL FREE ACCESS

2005 Volume 98 Issue 3 Pages 319-322

DOI https://doi.org/10.1254/jphs.SC0050033

View "Advance Publication" version (June 19, 2005).

Details

Abstract

Histamine H₄ receptor is considered as a novel therapeutic target for allergic diseases. To enhance the knowledge about species difference, which is essential for drug discovery research, monkey H₄ receptor was identified. Monkey H₄ receptor was characterized to have comparable similarity with its human counterpart. Discovery of monkey H₄ receptor will contribute to a better interpretation of effective drug discovery.

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