Comparison of self-report and structured clinical interview in the identification of depression

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Abstract

Background

A self-report method seeking a binary response for assessing depression is a cost-effective and time-efficient way to obtain a psychiatric history, yet the reliability of this method is largely unknown. The aim of the study was to compare and assess the validity of two methods for identifying a past history of depression in a population-based study.

Methods

This study examined data collected from 891 men and 1086 women participating in the Geelong Osteoporosis Study. Self-reports of depression were compared with results obtained using the Structured Clinical Interview for DSM-IV-TR Research Version, Non-patient edition (SCID-I/NP).

Results

Using the SCID-I/NP, 146 (16.4%) men and 285 (26.2%) women met criteria for a lifetime depression. Of those participants, 61.0% (n = 263) self-reported a history of depression. The level of agreement between self-reporting depression and the SCID-I/NP depression module was reasonably high; 61% sensitivity, 89.5% specificity and the overall level of agreement (kappa) was 0.5.

Limitations

Results may not be generalizable to other self-report instruments or be suitable for use in clinical samples.

Conclusion

The SCID-I/NP remains the gold standard for identifying depression; however, given the moderate level of agreement between the self-report questionnaire and SCID-I/NP in our current study, we conclude that simple self-report methods can be used to identify depression with some degree of confidence.

Introduction

Self-report methods and symptom scales are often utilised to obtain diagnostic information in large-scale epidemiological studies, as they are cost-effective and time-efficient. There are many simple scales available to measure symptoms of depression that are either self-administered or administered by a lay person. The number of items on a depression symptom scale can vary, however, scales with as little as two-items have been successfully utilised to detect depression [1]. Research comparing depressive symptoms measured using such convenient survey instruments and results from ‘gold standard’ psychiatric examinations, such as the Structured Clinical Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV) (SCID-I), report varying levels of agreement among clinical and survey settings [2].

Simple self-report methods that seek a binary (yes/no) response have been used to ascertain the presence of medical conditions in a medical history exam. Past research has shown good sensitivity and specificity for self-reported medical conditions against physician reports for well-defined chronic conditions, such as hypertension, whereas over-reporting has been identified with conditions such as arthritis [3].

A self-report yes/no questionnaire assessing psychiatric disorders is an effective way to obtain information regarding psychiatric history, yet the reliability of this method remains in question. One study, the Segiumiento Universidad de Navarra (SUN) project [4], compared self-reported physician diagnosis of depression with the SCID-I in a group of university graduates. In that study, the clinical assessment confirmed depression in 74% of those with a self-reported diagnosis [4].

This current analysis is a head-to-head comparison of a simple, self-reported identification method for lifetime depression compared against a gold-standard clinical psychiatric assessment, using data from a large, randomly-selected, population-based sample of men and women.

Section snippets

Participants

This study utilised data collected as part of the Geelong Osteoporosis Study (GOS), which is an on-going, population-based study of Australian men and women randomly-selected from electoral rolls for the region (Barwon Statistical Division, South-Eastern Australian). Initially, 1494 women (20–94 years) and 1540 men (20–93 years) were enrolled between 1994–1997 and 2001–2006, respectively and have returned for ongoing assessment. Details of non-participation have been published elsewhere [5], [6].

Results

The median age of the whole group was 54.9 years, comprising 45% men, 13% smokers and 10% antidepressant users (Table 1). The spread of SES was relatively even, with approximately 20% in each of the SES categories as measured by IRSAD, and just over half of participants (54.1%) had completed secondary school or held a post-secondary school qualification. A total of 146 (16.4%) men and 285 (26.2%) women met SCID-I/NP criteria for lifetime depression; the most common being major depressive

Discussion

The overall level of agreement between self-report depression and clinically determined depression using the SCID/NP was moderate to good, with 61% of the study population identified as having a history of depression using the SCID/NP also self-reporting past depression.

Previous studies comparing depressive symptom survey instruments and ‘gold standard’ clinician-administered measures report varying results. In support of our study, the SUN project reported a sensitivity of 74% and specificity

Conclusion

The SCID-I remains a ‘gold standard’ tool for identifying incident depression. However, simple, self-report measures of lifetime depression can be used with some degree of confidence given the high level of agreement with the SCID-I/NP in the current study.

Acknowledgment

The study was funded by the National Health and Medical Research Council (NHMRC) of Australia. The authors acknowledge the men and women who participated in the study.

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