Improving maintenance of physical activity in older, knee osteoarthritis patients trial-pilot (IMPACT-P): Design and methods☆
Section snippets
Introduction/background
Symptomatic knee osteoarthritis (OA) is a prevalent chronic degenerative disease that acts as a primary cause of activity restriction and physical disability among older adults [1]. There is considerable evidence that inactivity, secondary to the primary OA symptoms, exacerbates pain symptoms and accelerates progression toward disability in older knee OA patients [2], [3]. Given that traditional surgical and pharmacologic treatments are associated with mixed success and adverse long-term side
Overview
The Improving Maintenance of Physical Activity in Osteoarthritis Trial-Pilot (IMPACT-P) was a two-arm, single-blind randomized controlled pilot trial designed to investigate the comparable efficacy of two exercise interventions (TRAD and GMCB exercise interventions). A total of 80 older adults with radiographic evidence of symptomatic knee OA were randomly assigned to either the GMCB (n = 40) or traditional exercise intervention (n = 40) arms. Assessments of the primary and secondary outcomes were
Discussion
The IMPACT-P trial was a single-blind, two arm randomized controlled pilot trial evaluating the comparable efficacy of traditional exercise intervention with that of a social cognitive theory-based GMCB exercise intervention for producing improvements in physical activity participation and select relevant knee OA outcomes. Although exercise is now advocated as an important component in the medical management of knee OA, challenges in successfully promoting long-term maintenance of regular
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Support for the present study was provided by NIH/NIAMS grant # R21 AR054595.