Thrombin generation tests
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Cited by (143)
A specific fluorescence resonance energy quenching–based biosensor for measuring thrombin activity in whole blood
2024, Journal of Thrombosis and HaemostasisAntithrombin activity and central venous catheter-associated thrombosis in critically ill children at high risk of bleeding
2024, Journal of Thrombosis and HaemostasisElevated thrombin generation levels in the left atrial appendage in patients with atrial fibrillation
2023, Research and Practice in Thrombosis and HaemostasisSelective modulator of nuclear receptor PPARγ with reduced adipogenic potential ameliorates experimental nephrotic syndrome
2022, iScienceCitation Excerpt :We thus measured thrombin generation parameters in our model of NS, their alteration with treatment with Pio and GQ-16, and correlation with proteinuria. A typical thrombin generation curve, as shown in Figure 5A, is characterized by a short lag phase, the area under the curve (endogenous thrombin potential), peak thrombin, and velocity index (Castoldi and Rosing, 2011). Representative curves from each of the study groups are shown in Figure 5B. Endogenous thrombin potential (ETP) is a consistently elevated thrombin generation parameter in NS (Kerlin et al., 2015; Waller et al., 2020), and we found it to be significantly increased in nephrotic rats (PAN, 3646 ± 199 nM∗min vs. Control, 2445 ± 402 nM∗min; p = 0.014) (Figures 5B and 5C).
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