Skip to main content

Advertisement

SpringerLink
Log in

Fatal calciphylaxis in two patients with giant cell arteritis

  • Case Report
  • Published:
Clinical Rheumatology Aims and scope Submit manuscript

Abstract

Two elderly female patients with fatal calciphylaxis, despite nearly normal renal functions, occurring during treatment for giant cell arteritis, are described. The possible mechanisms for this association are discussed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4

References

  1. Blockmans D, De Ceuninck L, Vanderschueren S, Knockaert D, Mortelmans L, Bobbaers H (2006) Repetitive 18F-fluorodeoxyglucose positron emission tomography in giant cell arteritis: a prospective study in 35 patients. Arthritis Rheum 55(1):131–137

    Article  PubMed  Google Scholar 

  2. Selye H, Gabbiani G, Strebel R (1962) Sensitisation to calciphylaxis by endogenous parathyroid hormone. Endocrinology 71:554–558

    Article  PubMed  CAS  Google Scholar 

  3. Grob J, Legre R, Bertocchio P et al (1989) Calcifying panniculitis and kidney failure. Considerations on pathogenesis and treatment of calciphylaxis. Int J Dermatol 28:129–131

    PubMed  CAS  Google Scholar 

  4. Fischer AH, Morris DJ (1995) Pathogenesis of calciphylaxis: study of three cases with literature review. Hum Pathol 26:1055–1064

    Article  PubMed  CAS  Google Scholar 

  5. Edelstein CL, Wickham MK, Kirby PA (1992) Systemic calciphylaxis presenting as a painful, proximal myopathy. Postgrad Med J 68:209

    Article  PubMed  CAS  Google Scholar 

  6. Mehta RL, Scott G, Sloand JA, Francis CW (1990) Skin necrosis associated with acquired protein C deficiency in patients with renal failure and calciphylaxis. Am J Med 88:252–257

    Article  PubMed  CAS  Google Scholar 

  7. Zacharias JM, Fontaine B, Fine A (1999) Calcium use increases risk of calciphylaxis: a case-control study. Perit Dial Int 19:248–252

    PubMed  CAS  Google Scholar 

  8. Korkmaz C, Dundar E, Zubaroglu I (2002) Calciphylaxis in a patient with rheumatoid arthritis without renal failure and hyperparathyroidism: the possible role of long-term steroid use and protein S deficiency. Clin Rheumatol 21:66–69

    Article  PubMed  CAS  Google Scholar 

  9. Rubinger D, Friedlaender MM, Silver J, Kopolovic Y, Czaczkes WJ, Popovtzer MM (1986) Progressive vascular calcification with necrosis of extremities in hemodialysis patients: a possible role of iron overload. Am J Kidney Dis 7:125–129

    PubMed  CAS  Google Scholar 

  10. Blockmans D, Stroobants S, Maes A, Mortelmans L (2000) Positron emission tomography in giant cell arteritis and polymyalgia rheumatica: evidence for inflammation of the aortic arch. Am J Med 108:246–249

    Article  PubMed  CAS  Google Scholar 

  11. Nordborg E, Bengtsson BA, Petursdottir V, Nordborg C (1997) Morphological aspects of giant cells in giant cell arteritis: an electron-microscopic and immunocytochemical study. Clin Exp Rheumatol 15:129–134

    PubMed  CAS  Google Scholar 

  12. Nordborg C, Nordborg E, Petursdottir V, Fyhr IM (2001) Calcification of the internal elastic membrane in temporal arteries: its relation to age and gender. Clin Exp Rheumatol 19:565–568

    PubMed  CAS  Google Scholar 

  13. Al-Absi AI, Wall BM, Cooke CR (2004) Medial arterial calcification mimicking temporal arteritis. Am J Kidney Dis 44:e73–e78

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of General Internal Medicine, University Hospital Gasthuisberg, Dienst Algemene Inwendige Geneeskunde, UZ Gasthuisberg, Herestraat 49, 3000, Leuven, Belgium

    K. Brouns, H. Bobbaers & D. Blockmans

  2. Department of Pathology, University Hospital Gasthuisberg, Leuven, Belgium

    E. Verbeken

  3. Department of Dermatology, University Hospital Gasthuisberg, Leuven, Belgium

    H. Degreef

Authors
  1. K. Brouns
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. E. Verbeken
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. H. Degreef
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. H. Bobbaers
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. D. Blockmans
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to D. Blockmans.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Brouns, K., Verbeken, E., Degreef, H. et al. Fatal calciphylaxis in two patients with giant cell arteritis. Clin Rheumatol 26, 836–840 (2007). https://doi.org/10.1007/s10067-006-0366-3

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10067-006-0366-3

Keywords

Search

Navigation