Abstract
Hyperimmunoglobulinemia D syndrome (HIDS) is newly recognized and resembles familial Mediterranean fever (FMF). It is inherited as an autosomal recessive trait. Mutation of the gene coding for mevalonate kinase is responsible for the disease. The gene is located at chromosome 12q24. The patients initially described were of Dutch ancestry. Other cases from Turkey and Armenia were reported. The case we present is the first from Arab countries to be registered in the International HIDS Registry and to our knowledge the first to be reported.
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Acknowledgements
I would like to extend my appreciation and thanks to Dr. Ina Klasen and Dr. Anna Simon from the University Medical Center, Nijmegen, the Netherlands for their help in performing IgD level and DNA sequence analysis at their medical center for this patient.
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Hammoudeh, M. Hyperimmunoglobulinemia D syndrome in an Arab child. Clin Rheumatol 24, 92–94 (2005). https://doi.org/10.1007/s10067-004-0953-0
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DOI: https://doi.org/10.1007/s10067-004-0953-0