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Sacroiliitis and severe disability due to isotretinoin therapy

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Abstract

We report a case of acute sacroiliitis with severe disability after only 3 weeks of isotretinoin therapy with graduate reduction of pain, limitation and muscle incompetence after discontinuation of the drug and ACTH-depo injection and Ethodolac therapy. Naranjo probability scale indicated a probable relationship between isotretinoin therapy and bilateral sacroiliitis. We discussed possible mechanisms of sacroiliitis and disability due to isotretinoin treatment.

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Correspondence to Alexander P. Rozin.

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Rozin, A.P., Kagna, O. & Shiller, Y. Sacroiliitis and severe disability due to isotretinoin therapy. Rheumatol Int 30, 985–986 (2010). https://doi.org/10.1007/s00296-009-1014-4

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  • DOI: https://doi.org/10.1007/s00296-009-1014-4

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