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Cryptogenic organizing pneumonia associated with primary Sjogren’s syndrome

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Abstract

The association of cryptogenic organizing pneumonia (COP) with primary Sjogren’s syndrome (PSS) is extremely rare. We report a case of  simultaneous diagnosis of  PSS and COP. A 70-year-old female presented with fever, non-productive cough and dyspnea of  2 months’ duration. She had experienced sicca symptoms for the past 2 years. The chest radiograph revealed a right lower lobe infiltrate, which was unresponsive to antibiotics. Bronchoscopy, bronchoalveolar lavage and an open lung biopsy established the diagnosis of COP, while a lip biopsy was consistent with PSS. The patient improved on steroids. Organizing pneumonia may be one of  the early manifestations of  PSS. Exclusion of PSS should be part of  a thorough evaluation of  the patient with COP.

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Authors and Affiliations

  1. Department of  Pathophysiology, University of  Athens Medical School, Laiko University Hospital, 75, M. Asias Street, Athens, 11527, Greece

    Savvas Ioannou, Sophie P. Toya & George E. Tzelepis

  2. Department of Thoracic Surgery, University of Athens Medical School, Laiko University Hospital, Athens, Greece

    Periklis Tomos

Authors
  1. Savvas Ioannou
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  2. Sophie P. Toya
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  3. Periklis Tomos
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  4. George E. Tzelepis
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Correspondence to Sophie P. Toya.

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Ioannou, S., Toya, S.P., Tomos, P. et al. Cryptogenic organizing pneumonia associated with primary Sjogren’s syndrome. Rheumatol Int 28, 1053–1055 (2008). https://doi.org/10.1007/s00296-008-0568-x

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  • DOI: https://doi.org/10.1007/s00296-008-0568-x

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