Patient demographic and clinical characteristics at index visit/baseline*.
| Characteristics | Incident Malignancy, n = 880 |
|---|---|
| Sex, n | 878 |
| Female | 592 (67.4) |
| Age, n | 878 |
| Mean (SD), median (IQR) | 66.6 (10.5), 67 (59–74) |
| Duration of RA, n | 878 |
| Mean (SD), median (IQR) | 14.1 (10.7), 11 (6–20) |
| Race, n | 864 |
| White | 792 (91.7) |
| African American | 47 (5.4) |
| Asian | 9 (1) |
| Other | 16 (1.9) |
| Education, n | 844 |
| College or above | 471 (55.8) |
| Smoking status, n | 878 |
| Never smoker | 395 (45) |
| Previous smoker | 349 (39.7) |
| Current smoker | 134 (15.3) |
| Weight, lbs, n | 880 |
| Mean (SD), median (IQR) | 172.7 (41.4), 170 (145–195) |
| BMI, n | 877 |
| Underweight | 21 (2.4) |
| Normal weight | 268 (30.6) |
| Overweight | 312 (35.6) |
| Obese | 276 (31.5) |
| Work status, n | 859 |
| Full-time | 174 (20.3) |
| Part-time | 64 (7.5) |
| At home | 73 (8.5) |
| Student | 9 (1) |
| Disabled | 111 (12.9) |
| Retired | 428 (49.8) |
| Insurance, n | 862 |
| None | 3 (0.3) |
| Private | 581 (67.4) |
| Medicaid | 43 (5) |
| Medicare | 464 (53.8) |
| RF/CCP status, n | 602 |
| Positive | 468 (77.7) |
| Comorbid conditions, n | 880 |
| History of CVD | 68 (7.7) |
| History of serious infection | 75 (8.5) |
| Solid cancer type, n | 880 |
| Breast cancer | 190 (21.6) |
| Lung cancer | 78 (8.9) |
| Melanoma skin cancer | 83 (9.4) |
| Prostate cancer | 61 (6.9) |
| Uterus and ovary cancer | 36 (4.1) |
| Colon cancer | 33 (3.8) |
| Bladder cancer | 20 (2.3) |
| Thyroid cancer | 17 (1.9) |
| Other cancer | 362 (41.1) |
| CDAI, n | 858 |
| Mean (SD), median (IQR) | 11.2 (12.1), 8 (3–16) |
| CDAI categories, n | 858 |
| Remission | 218 (25.4) |
| Low | 311 (36.2) |
| Moderate | 197 (23.0) |
| High | 132 (15.4) |
| Period of cancer diagnosis, n | 880 |
| 2002–2006 | 124 (14.1) |
| 2007–2012 | 491 (55.8) |
| 2013–2016 | 265 (30.1) |
Values are n (%) unless otherwise specified.
↵* The index date is the first Corrona visit following a malignancy diagnosis, or the enrollment visit for those with a history of malignancy prior to enrollment. Variable reported at index date, unless otherwise noted. IQR: interquartile range; BMI: body mass index; RF: rheumatoid factor; CCP: cyclic citrullinated peptide; CVD: cardiovascular disease; CDAI: Clinical Disease Activity Index; RA: rheumatoid arthritis.