NCM and pulmonary function per patient diagnosis group.
| N | Primary RP, n | Secondary RP | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| No definite diagnosis, n | Definite diagnosis, n | ||||||||||
| Early SSc | ipSS | iSLE | UCTD | Other | SSc | pSS | SLE | MCTD | RA | ||
| 245 | 195 | 5 | 42 | 41 | 109 | 40 | 30 | 30 | 7 | 15 | |
| NCM patterns, n (%) | |||||||||||
| Normal | 245 (100) | 4 (2) | 4 (80) | 31 (74) | 27 (66) | 0 (0) | 3 (8) | 11 (37) | 16 (53) | 2 (29) | 11 (73) |
| Nonspecific | 0 (0) | 2 (1) | 1 (20) | 11 (26) | 14 (34) | 109 (100) | 2 (5) | 9 (30) | 9 (30) | 0 (0) | 2 (13) |
| Early | 0 (0) | 115 (59) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 12 (30) | 7 (23) | 2 (7) | 2 (29) | 1 (7) |
| Active | 0 (0) | 74 (38) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 23 (56) | 3 (10) | 3 (10) | 3 (43) | 1 (7) |
| NCM specifics, median (IQR) or n (%) | |||||||||||
| Capillaries per 3 mm per finger | 23.3 (21.7–24.5) | 21.0 (18.5–23.0) | 23.5 (22.8–24.5) | 22.8 (21.0–24.0) | 23.1 (21.8–24.7) | 22.7 (21.0–23.5) | 18.5 (14.0–19.8) | 23.3 (21.3–24.8) | 21.5 (19.8–23.0) | 20.3 (16.5–23.0) | 23.5 (21.3–24.8) |
| No. patients with giants | 0 (0) | 188 (97) | 0 (0) | 0 (0) | 0 (0) | 0 (0) | 35 (88) | 10 (33) | 5 (17) | 5 (71) | 2 (13) |
| No. patients with loss of capillaries | 0 (0) | 37 (19) | 0 (0) | 1 (2) | 0 (0) | 9 (8) | 15 (40) | 2 (7) | 4 (14) | 2 (29) | 1 (7) |
| No. patients with hemorrhages | 13 (5) | 44 (23) | 0 (0) | 4 (10) | 2 (5) | 11 (10) | 13 (32) | 3 (10) | 3 (10) | 2 (29) | 2 (13) |
| PFT, n (%) | |||||||||||
| Abnormal PFT | 4 (2) | 29 (15) | 0 (0) | 6 (14) | 3 (8) | 3 (2) | 18 (45) | 4 (13) | 7 (23) | 3 (43) | 2 (13) |
| DLCO < 70% | 4 (2) | 27 (14) | 0 (0) | 6 (14) | 2 (5) | 3 (2) | 14 (35) | 4 (13) | 6 (20) | 1 (14) | 0 (0) |
| FVC < 70% | 0 (0) | 2 (1) | 0 (0) | 1 (2) | 1 (3) | 0 (0) | 3 (8) | 0 (0) | 3 (10) | 1 (14) | 1 (7) |
NCM: nailfold capillary microscopy; PFT: pulmonary function tests; SLE: systemic lupus erythematosus; iSLE: incomplete SLE; pSS: primary Sjögren syndrome; ipSS: incomplete pSS; MCTD: mixed connective tissue disease; UCTD: undifferentiated CTD; RA: rheumatoid arthritis; RP: Raynaud phenomenon; SSc: systemic sclerosis; IQR: interquartile range; FVC: forced vital capacity.