Table 1.

Phases of the development of the Shoulder Core Domain Set and included domains.

Circle	Preliminary Core Set OMERACT 2016	Proposed Core Set OMERACT 2018	Final Approved Core Set OMERACT 2018	Delphi^{^§,9}	Confidence in the Evidence from Qualitative Evidence Synthesis^{^±,10}
Inner	Pain	Pain	Pain	97%	Moderate
	Physical function/activity	Physical function/activity	Physical function/activity	94%	Moderate
	Global perceived effect	Global perceived effect	Patient global — shoulder	86%	NA
	Adverse events	Adverse events including death	Adverse events including death	NA	NA
Middle	Participation (recreation and work)	Participation (recreation and work)	Participation (recreation and work)	NA; work ability 90%; recreation 71%	Moderate
	Sleep	Sleep	Sleep	70%	Moderate
	Emotional well-being	Emotional well-being	Emotional well-being	69%	Moderate/low^*
	—	Condition-specific pathophysiological manifestations	Condition-specific pathophysiological manifestations	Voted out (< 67%)	Low
Outer	Research agenda	Cognitive dysfunction		NA	Very low

↵§ Percentage of votes from the Delphi second round agreeing with the inclusion of the domain⁹.
↵± Confidence in each review finding (high, moderate, low, very low) using the GRADE-CERQual approach¹¹; data from the qualitative evidence synthesis¹⁰.
↵* Moderate for frustration and anxiety and low for depression. OMERACT: Outcome Measures in Rheumatology; NA: not available, i.e., not included in the Delphi or in the qualitative evidence synthesis; GRADE-CERQual: Confidence in the Evidence from Reviews of Qualitative research.