Unadjusted and adjusted all-cause HRU in the followup period1.
| Variables | Unadjusted Analysis | Adjusted Analysis | |||
|---|---|---|---|---|---|
| Patients with SSc, n = 2192 | Matched Controls, n = 2192 | p | Patients with SSc vs Matched Controls | p | |
| Proportion of patients with visits or admissions, n (%) | OR (95% CI) | ||||
| Any IP admission | 688 (31.4) | 238 (10.9) | < 0.0001 | 3.8 (3.2–4.5) | < 0.0001 |
| Any ER visit | 698 (31.8) | 425 (19.4) | < 0.0001 | 1.9 (1.7–2.2) | < 0.0001 |
| Any OP visit2 | 2181 (99.5) | 1851 (84.4) | < 0.0001 | – | – |
| Any other visits3 | 915 (41.7) | 531 (24.2) | < 0.0001 | 2.2 (2.0–2.6) | < 0.0001 |
| Annual no. visits or admissions, mean (SD) | IRR (95% CI) | ||||
| IP admissions | 0.7 (2.1) | 0.3 (2.3) | < 0.0001 | 2.4 (2.2–2.6) | < 0.0001 |
| Total IP hospitalization days | 3.7 (12.7) | 1.1 (6.7) | < 0.0001 | 3.1 (2.9–3.4) | < 0.0001 |
| ER visits | 0.7 (2.5) | 0.3 (1.2) | < 0.0001 | 2.0 (1.9–2.2) | < 0.0001 |
| OP visits | 23.8 (19.4) | 10.3 (12.4) | < 0.0001 | 2.3 (2.2–2.4) | < 0.0001 |
| Other visits3 | 3.0 (7.6) | 1.0 (3.4) | < 0.0001 | 2.9 (2.7–3.1) | < 0.0001 |
↵1 The followup period was defined as the 12-month period following the index date.
↵2 Model could not converge because 99.5% of patients with SSc had any OP visit.
↵3 Including laboratory tests and medical services at home. HRU: healthcare resource utilization; SSc: systemic sclerosis; IP: inpatient; ER: emergency room; OP: outpatient; IRR: incidence rate ratio.