Items | Nonbiologic Group | |||||||||
---|---|---|---|---|---|---|---|---|---|---|
Biologic Group | ||||||||||
SRM | Pearson’s Correlation | SRM | Pearson’s Correlation | |||||||
Total MRI Score | Clinical Score | No. Cases | Correlation of Change Scores | p | Total MRI Score | Clinical Score | No. cases | Correlation of Change Scores | p | |
All cases | 0.67 | – | 17 | – | – | 0.58 | – | 18 | – | – |
Active joint count | 0.67 | 0.40 | 17 | 0.72 | 0.00 | 0.58 | 0.45 | 18 | 0.22 | 0.37 |
Swollen joint count | 0.67 | 0.50 | 17 | 0.41 | 0.10 | 0.58 | 0.36 | 18 | 0.07 | 0.77 |
Enthesitis count | 0.67 | 0.74 | 17 | 0.42 | 0.09 | 0.58 | 0.37 | 18 | 0.02 | 0.93 |
Schober | 0.67 | 0.24 | 17 | 0.36 | 0.16 | 0.58 | 0.00 | 18 | 0.10 | 0.69 |
Hip abduction | 1.13 | −1.30 | 9 | 0.08 | 0.85 | 0.37 | −0.38 | 10 | 0.17 | 0.61 |
FABER | 0.67 | 0.42 | 17 | 0.58 | 0.01 | 0.58 | 0.24 | 18 | 0.23 | 0.34 |
SI joint tenderness | 0.67 | 0.33 | 17 | 0.48 | 0.05 | 0.58 | 0.43 | 18 | 0.22 | 0.36 |
ESR | NC | NC | NC | NC | NC | 0.36 | −0.13 | 8 | 0.71 | 0.05 |
CRP | NC | NC | NC | NC | NC | 0.36 | 0.26 | 11 | 0.36 | 0.29 |
PGA | 0.55 | 0.28 | 12 | 0.61 | 0.03 | NC | NC | NC | NC | NC |
BASDAI | 0.52 | 0.11 | 11 | 0.27 | 0.44 | 0.38 | 0.54 | 8 | 0.09 | 0.80 |
BASFI | 0.52 | −0.23 | 11 | 0.45 | 0.17 | 0.37 | 0.42 | 8 | 0.37 | 0.30 |
Change scores were calculated by subtracting final score from initial score to produce positive treatment-related change, as per convention. All 4 readings were pooled, not averaged, in calculating the SPARCC score change. SPARCC score SRM was recalculated for each clinical measure comparison by pairwise deletion of cases with missing clinical measure data. SPARCC: Spondyloarthritis Research Consortium of Canada; MRI: magnetic resonance imaging; SRM: standardized response mean; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; BASDAI: Bath Ankylosing Spondylitis Disease Activity Index; BASFI: Bath Ankylosing Spondylitis Functional Index; PGA: physician’s global assessment; SI: sacroiliac; FABER: Flexion, ABduction, and External Rotation; NC: not calculated due to insufficient observations (n < 6).